ID E4UQ84_ARTGP Unreviewed; 1437 AA.
AC E4UQ84;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=MGYG_02177 {ECO:0000313|EMBL:EFQ99165.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989823; EFQ99165.1; -; Genomic_DNA.
DR RefSeq; XP_003174648.1; XM_003174600.1.
DR STRING; 535722.E4UQ84; -.
DR GeneID; 10029945; -.
DR VEuPathDB; FungiDB:MGYG_02177; -.
DR eggNOG; ENOG502REBM; Eukaryota.
DR HOGENOM; CLU_002541_1_0_1; -.
DR InParanoid; E4UQ84; -.
DR OMA; MFAREQK; -.
DR OrthoDB; 2788168at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR CDD; cd13278; PH_Bud4; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR012966; AHD.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR36100; BUD SITE SELECTION PROTEIN 4; 1.
DR PANTHER; PTHR36100:SF1; BUD SITE SELECTION PROTEIN 4; 1.
DR Pfam; PF08174; Anillin; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 1218..1339
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 666..697
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 746..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 829..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1041..1070
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1366..1437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..195
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..355
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 370..399
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..501
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..550
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 830..910
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1366..1385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1437
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1437 AA; 159306 MW; F87D063D15742435 CRC64;
MGPGQRPLSE LSPVAHKRNS PSWKDPASNE SSPFENSPLS NATSPRRFWQ GRDAGSPYRP
GHENSDPYDG SPRTPAASKR SSIENLMRAS RVKNSSMFAR EHKQEYDPTH IQVLERPLAS
GRPLSRQFQN SQDGTSQIDA RRQLPSQSAG FRHSGEGVGA SPSTTKSGDE DASSPIKSPT
SQSPGKSSLS KASRFDRGSA SFDPRREIWS DDGDESRVSM TSEGYSYHRQ TKSVTFDAAP
PQVNEYEMTT PVPSSVASSS REGSFEDASN EDSFDHSYSM EIEDSFDASL EDTDKTPVVL
PDEWRYMSPD SANDETVGSD GDPFNDDFGS PGPDIRPSSR DSTLFKNRIE SLDSNGERRP
LPPLPPSQST PQTSRSSPSS GLNAAFERGS STQRDMPQPL RPASCSKLDI ASPSRSSLSL
EDRLKLMMSG EHSYQSDAET QRERRMRRAG AKERSVERDL DHSHNSENHD ESTAIESPRI
SRESILKNIK RQEESSELSD YHDTSHGSGN YNSLPLDPDV PIPSLETDQL FEDETVIIKE
EEDEDDIDLY SVPSFVENDT NDESGHAEMQ GHVVDDSSSR YSDTSKDDLP TPPGGTLHSF
DMGSGELTPT KAVHSPRYPE HDLLASSMSG ADADPNFDVQ FTSYIDQSTP PAEDRLAQPP
RIELENIRNS LDRPGSPDSV IRHPISPAES PDQSLIVPEP IATIKAPGGT YKTRTSLTPA
DVNTMAATRR RVSGQDVPVS PIEEFKPLPR VEQSTKEEES NVAEEPKEHK EHQEHKPLEL
APLPEKSRIS SLVKLDIKMD SGSDGFGLDA EFDRVMEAQK VAFDIPFSQD PTQALDTGSS
AQKTPSTTFD RNTADTTTTK QRGYLMRQNT KMVVATSRPE DDGNTESLAA PSSPRKASQQ
TWTTEPWTPK ARRQSIKMAG SIPRKTIAEE PAPPLPGQES TVKDASKGTE EAAEAEAGDA
GDNAGEDADR GRLFVKVVGA KDLDLPLPRG ERSYFSLTLD NGLHCVTTSC LELGRSAPIG
QEFELVVMQE LEFQLTLQMK PDQIKPKPQP VRPASPAKAP KPQKSSAFSR VFASPKKRRE
MELRQQQEAQ QLQKRQAEEK ALANIIDPWE RVRKIVDKDG NFARAYVSLA DFEEKAFGRP
LTVDVTCFNE WAIDETVSSV KSKRSTATTV SRRPPYKIGT LELQLLYVPK PKGATDDDMP
KSMNACIREM RDADHAAARS WEGFLSQQGG DCPYWRRRLF KLQGSKLTAF HEVTRQPRAT
INLAKAVKLI DDRSSLTQKE TSAKGGRRRK SAFAEEEEGY MFVEEGFRIR FGNGEVIDFY
ADSRVEKDGW MKVLSETVGK GHSSGSGQAK PWTDLVLRRE KNLNIKRAVE EKKPPTVEER
KLVRHSYAPP PPPKEQHIGQ TRPTPGAIPR PRHQPQLSQP NISSQEARRQ KTRSLIF
//
