ID   E4V2T6_ARTGP            Unreviewed;       726 AA.
AC   E4V2T6;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 57.
DE   SubName: Full=IBR domain-containing protein {ECO:0000313|EMBL:EFR04310.1};
GN   ORFNames=MGYG_07317 {ECO:0000313|EMBL:EFR04310.1};
OS   Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS   gypseum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX   NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN   [1] {ECO:0000313|Proteomes:UP000002669}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS989828; EFR04310.1; -; Genomic_DNA.
DR   RefSeq; XP_003170073.1; XM_003170025.1.
DR   AlphaFoldDB; E4V2T6; -.
DR   STRING; 535722.E4V2T6; -.
DR   GeneID; 10025308; -.
DR   VEuPathDB; FungiDB:MGYG_07317; -.
DR   eggNOG; KOG1812; Eukaryota.
DR   HOGENOM; CLU_022733_0_0_1; -.
DR   InParanoid; E4V2T6; -.
DR   OMA; CCLNQIP; -.
DR   OrthoDB; 251172at2759; -.
DR   Proteomes; UP000002669; Unassembled WGS sequence.
DR   GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR   CDD; cd20335; BRcat_RBR; 1.
DR   CDD; cd22584; Rcat_RBR_unk; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR031127; E3_UB_ligase_RBR.
DR   InterPro; IPR002867; IBR_dom.
DR   InterPro; IPR044066; TRIAD_supradom.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR11685:SF457; TRANSLATION TERMINATION INHIBITOR PROTEIN ITT1; 1.
DR   Pfam; PF01485; IBR; 1.
DR   SUPFAM; SSF57850; RING/U-box; 2.
DR   PROSITE; PS51873; TRIAD; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          166..368
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51873"
FT   REGION          73..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..428
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          644..726
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..110
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        644..671
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..726
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   726 AA;  82267 MW;  E8745C130FFCA74B CRC64;
     MSVPQLTRDL EAPLQGLVDD ADRLAEWPEL VGLEDLLLDN GQLPSHRADR PCPQELHVFP
     DDVSPELLQI ISQPLETEQP PRSADRHSGN EDGRSQPPPS SYTGDDRSSL PVRTQAPAVK
     DHTRDNHLER CLSPESTATG ATFSRMGHKA TKETKNLKLR LLERNNFREC ASCFVELLDK
     NLVPLSCSHK YCLSCFSGMI ETAINNESKF PPKCCLEDIP TKLILHNVDS VLREEYKLKA
     QEYAIPRMSR WYCPSPNCGK WIPPKKIKLG APTQKCPICK WSICTACQRT AHQNNEHCPQ
     APYPERIDSI ASNGWRRCYK CQAMVDLTAD SGSVVCHCGA EFCCFCGARG GTCGCVQPSQ
     YGTKSRAESD TIMHRERAQL AAIVKENERS ERREVEERLR KEDTQKLPDG DGQRRQDDGR
     RRVQHDKEMK RLISIANQIQ KLQGELAKIN KIQQSMIIDR HQDSAQQIQV AAVSKQADFD
     QTRVKLEKAY ESNFKLRKSA LEVRQNATKL ELRTRQEEDE DDNFVQMQRH LKGKPNREER
     EKVILDKLNA SHKREQDALD KSHKEEMSEL EYHGSLESSA LQSGIMKKLG DLQRETNFTL
     YELSSTVISD RRWFKVAVEK RYGLLEEHRM FLINGPDAIK DTATSSSRYS SANNSSHSGT
     TYSVTSGRET PQSPLSPPPV FTEFGYRRSG PDALKTGGDV IPGSRSRSMS RNGLRHVSSQ
     SQFLYR
//