ID E4V5Y2_ARTGP Unreviewed; 621 AA.
AC E4V5Y2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Calcineurin-like phosphoesterase domain-containing protein {ECO:0000259|Pfam:PF00149};
GN ORFNames=MGYG_09198 {ECO:0000313|EMBL:EFR05507.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
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DR EMBL; DS989830; EFR05507.1; -; Genomic_DNA.
DR RefSeq; XP_003169614.1; XM_003169566.1.
DR AlphaFoldDB; E4V5Y2; -.
DR STRING; 535722.E4V5Y2; -.
DR GeneID; 10024845; -.
DR VEuPathDB; FungiDB:MGYG_09198; -.
DR eggNOG; KOG4419; Eukaryota.
DR HOGENOM; CLU_019028_0_0_1; -.
DR InParanoid; E4V5Y2; -.
DR OMA; PISFYRV; -.
DR OrthoDB; 5490776at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR CDD; cd07407; MPP_YHR202W_N; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 2.
DR InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR InterPro; IPR006179; 5_nucleotidase/apyrase.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR014485; Pesterase_C1039.
DR InterPro; IPR041823; YHR202W_N.
DR PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR PANTHER; PTHR11575:SF43; SER_THR PROTEIN PHOSPHATASE FAMILY (AFU_ORTHOLOGUE AFUA_3G04160); 1.
DR Pfam; PF00149; Metallophos; 1.
DR PIRSF; PIRSF017316; Pesterase_C1039; 1.
DR SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 47..271
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT REGION 502..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 621 AA; 69598 MW; 9073F39D373D5615 CRC64;
MPSMQAPGRL FWTLEILAWP ESPLPVSPQA PDPIPAPLRD LAWGQLNFLH TTDVHGWYSG
HLQEPSFSAD WGDYVSFATR MREKAEAAGT DLLVIDTGDR VEGSGLYDSS EPKGVYSSEF
LKKQHIDLLC SGNHELYKQN TSEAELRTTV PNFKGNYIAS NIDITDPDSG EIVPLAQRFK
KFTTKIQGIR IMAFGFLFDF TGNYNNTVVT PVERAIKQDW FQEAIRDREV DLFLVIGHVP
AKSKEYAAIF TEIRSVQWDT PIQFFGGHHH IRDYVKYDSK AYSLASGRFM ETIGFASLSG
LKTANKRVSA AESSPTFTRR YIDNNLFSLY HHSGLNETTF HTPEGKKVTE DIQKARSVLK
LDHVYGCAPK TLWMSRAKYP SNDSVYSWLE KEVLPDSLRP HLRENTTALA LVNTGGIRFD
IFKGPFTHDG AFIVSPFINE FRYMKDVPYD KAVMVLKVLN KAANILAQGG FMPMNSSSLS
PPEQWSRDED FVVETGYAQL AHGADNEQNP LRDSDEPSLI PGYTTKDDGG TEGDDTVHAP
VSFYRSPNCI MSTITNGDSA TLPDTVDLLY LDFLEPWVTV ATKVVGIDFD PKKDAEAFMP
GVQMRTMLTT WASQHWSCPS A
//
