ID E4XC22_OIKDI Unreviewed; 633 AA.
AC E4XC22;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
GN ORFNames=GSOID_T00007674001 {ECO:0000313|EMBL:CBY09147.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY09147.1};
RN [1] {ECO:0000313|EMBL:CBY09147.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653035; CBY09147.1; -; Genomic_DNA.
DR AlphaFoldDB; E4XC22; -.
DR InParanoid; E4XC22; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00190; Tryp_SPc; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 1.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001314; Peptidase_S1A.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR PANTHER; PTHR24264:SF15; RIKEN CDNA 2210010C04 GENE; 1.
DR PANTHER; PTHR24264; TRYPSIN-RELATED; 1.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00722; CHYMOTRYPSIN.
DR SMART; SM00020; Tryp_SPc; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50240; TRYPSIN_DOM; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363034};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU363034};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU363034}.
FT DOMAIN 383..631
FT /note="Peptidase S1"
FT /evidence="ECO:0000259|PROSITE:PS50240"
SQ SEQUENCE 633 AA; 69116 MW; A88CD512E9C49D98 CRC64;
MKLSQLVLLS SSAEAAWRDK WVNKKLMFSA RSSGDMQNCL ETAKNTTIKH PIDLGKWSCS
DASSGTVSCK GSCLEEGKKG QWKKMEFSVF CKPTRPQPVR KKIKGPASCK KQRSCFENVQ
DSVVKHALKS ELDNQNIAHG YWGECRGSSS KETCRALCKE GYEPKWRSNA PVSLTLDCRK
GKKKLTPKTS AIHGELACKP SREQLCKQPE IETPQGSLSF YGRKGDHDER HVYDLVCNDG
SVVGQGECEN GFWGSSLGDW PNSCARFDCS QDDVNELYPL FNGQWKCTDD DGNKNCAPDC
NNPNSRVRWL VTCSAYGDKV GWHISSGQAF VSVDECLADG EEAPVSEFKQ TTKKLPPGLE
TCSQSINFPD GVDGARLLGG DRIVGGVTAD AHSMPWMALL GVKTSSGWVG QCAGSIIADR
WVVTAAHCCR NIVSITAKFG EHDRWGSSAD EFALTTTRMF IHPKYYDASD DGTKMNYDIC
LLRFDDNILD KAPNKEVVKT ACLPTEDVQH GDACWVGGWG AMRYGSGAAR VLQSVGVNIM
DHAYCENFSN SIIPRPDDIC ATTPDEDGDG KTDGGMDACQ GDSGGALICE RNGFANVVGV
VSRGNGCAWA GEPGLYTSTF VTRDWIRDIV SKN
//
