ID   E4XDS9_OIKDI            Unreviewed;       245 AA.
AC   E4XDS9;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   RecName: Full=Lipid droplet-associated hydrolase {ECO:0000256|ARBA:ARBA00019242};
DE   AltName: Full=Lipid droplet-associated serine hydrolase {ECO:0000256|ARBA:ARBA00031924};
GN   ORFNames=GSOID_T00008327001 {ECO:0000313|EMBL:CBY19318.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY19318.1};
RN   [1] {ECO:0000313|EMBL:CBY19318.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SUBCELLULAR LOCATION: Lipid droplet {ECO:0000256|ARBA:ARBA00004502}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. LDAH family.
CC       {ECO:0000256|ARBA:ARBA00008300}.
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DR   EMBL; FN653040; CBY19318.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4XDS9; -.
DR   InParanoid; E4XDS9; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   GO; GO:0005811; C:lipid droplet; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0019915; P:lipid storage; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR019363; LDAH.
DR   PANTHER; PTHR13390; LIPASE; 1.
DR   PANTHER; PTHR13390:SF0; LIPID DROPLET-ASSOCIATED HYDROLASE; 1.
DR   Pfam; PF10230; LIDHydrolase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Lipid droplet {ECO:0000256|ARBA:ARBA00022677};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307}.
SQ   SEQUENCE   245 AA;  27942 MW;  B849D485882191F8 CRC64;
     MAPRATSVCS LMESQEPEKK QKFEEQWIQY QGAWTQVISL KREDPTYSIV LISGNPGVAR
     FYSVFAEEIF KLCHCEIHVL SHSGMVSSVP PKKASIEKSK VLFHSQMKQK HYIIDQLGLY
     EHPKLVLMGH SIGARMMLDC IHENTLLAIG LTPTIERMSI TPRGKDLTPH FNSSIYGLSI
     FLNKTFNIFV FPAKKSPTQK HVFCSSLFLH PFNSASPCLA KIYKKSASNE RRNDQRCDCR
     RYVLS
//