ID E4XUX5_OIKDI Unreviewed; 341 AA.
AC E4XUX5;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Alcohol dehydrogenase-like N-terminal domain-containing protein {ECO:0000259|Pfam:PF08240};
GN ORFNames=GSOID_T00004840001 {ECO:0000313|EMBL:CBY13522.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY13522.1};
RN [1] {ECO:0000313|EMBL:CBY13522.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653193; CBY13522.1; -; Genomic_DNA.
DR AlphaFoldDB; E4XUX5; -.
DR InParanoid; E4XUX5; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43401; L-THREONINE 3-DEHYDROGENASE; 1.
DR PANTHER; PTHR43401:SF2; L-THREONINE 3-DEHYDROGENASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 27..134
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
SQ SEQUENCE 341 AA; 37309 MW; 2BD4DA933A0400D5 CRC64;
MQALVFTKAE KSLELKEVPK PKISKSTDVL VKISNCGVCG TDCHIFHGDI SNVGDVFVPG
HEAGGVVTAV GDDVTAVKVG DKVAIDPNKG CHGCNHCRNA NPHFCKKGSF NDAFGIFRNG
GFAEHAVVPE ESLYLVPENF NMSHMSLVEP LSCVVHGWRK LTAGRQIQTG AKILVQGAGI
IGSLWCCLMH FKGYRHVTVS EPSEERRGFI DGLQLGFKTT EPKGIEQDYD VVVDCSGAVR
AIQDGINRVA HGGIFLQFGV APSTATCEIR PFHIYEREIT IQGVMVNPWA FPEAIELTNQ
LRARYLDFAK LGIGKYKLDE YKECFDKLSS GKISKASFVF E
//
