ID E4Y3U3_OIKDI Unreviewed; 1634 AA.
AC E4Y3U3;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00018203001 {ECO:0000313|EMBL:CBY30341.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY30341.1};
RN [1] {ECO:0000313|EMBL:CBY30341.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; FN654275; CBY30341.1; -; Genomic_DNA.
DR Proteomes; UP000011014; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 2.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140:SF860; DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C; 1.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 4.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}.
FT DOMAIN 67..747
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1347..1592
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 599..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..649
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1201..1255
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 853..887
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 923..1079
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1209..1231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 161..168
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1634 AA; 185520 MW; 8059902C39E6143F CRC64;
MPNQSDIEAL YVKGARVWIP DPDTVWRPCR LAEDLNHSDD DDDEYNVVKF NLKKHGTPHL
RNPDVLLAEN DLTALSFLHE PAVLNSLKER FVHREQVYTY CGIVLVAINP YQACPIYDDT
FIELYSTRDN AELDPHIYSI ANSAFTNMTR FGKNQSIIVT GESGAGKTVS AKFSMKFFAQ
VGGSSGPTSG KDNVETKVLA SNPIMEAMGN AKTTRNDNSS RFGKYIELDF DSKNRVTGAA
MRTYLLEKSR VVRPGLNERN YHIFYQLVAA AQTDPQLASL HLKEVRDFTY LTAGECLEVD
NVDDAKEFSE TQYALTLLGV GSKEQSLILR VLAAILHIGN IEMTDSGNDS ASLDPAEKSL
GIVCTLMGVE SSQLCQWLIH RRIQTVTDVF DKPLRLEEAI SARDSLAKFI YAQLFEMIVY
QVNEALKTKT KSSNSIGVLD IYGFETFEVN SFEQFCINYA NEKLQQQFCQ HVFKLEQEEY
QKEKLNWTKI EFYDNQPCID LIEAKLGVLD LLDEECKMPK GSDDSWAMNL YNRHLKKHKN
FDKPRTSNSA FIIKHFADDV TYQVEDFVSK NRDAVNQEQV SILKGSKFDL VAKLFQEKAP
PSKKPARPGA RSKNLKSTVG RQFSDSLKSL MEKLNATTPH YVRCIKPNDE KAVFTFEPSR
SVEQLRACGV LETVRLSAAG FPGRWSYKDF RTRYRVLLRG KEPKMEPRKA CEAMLTRLIP
DEDKYAFGKT KIFFRAGQVA LMEKWRIDRL NHSASIIQKF IKMFIYRRQY LKKRAIALKI
QTAARAFLAR KQLRVYGLKR EQSAIVIQSV WRMYRARKLF LLNIRRVVRI QCLWRVKVAR
SRYRILRAEA RDVNKIKSLN KGLENKIMEL KRKSDDKAAK VKELEALLAK ADKSSELSDE
KAAEIVAQLG QVSNQRDELV KQSAEKDVRI QELEALLEEA NRQTAAAQNQ LTQSKNSKME
LEVESDKLRQ RAKTLDDDLL RLRSESELKV NEYKRQASQG TSDGAAELMS SQLIEKEQEL
NTLSQRYANL NDELQITRNR QGDQMIEVTA KYDTLQVELT HVKEENARLN AELTALTDAA
QESGGADVVM VRKNELLMKD LEAMREAQLT AQQQQAERKS RMRSTEMNTD EIDVTLIKAL
EAKVMNDQLE IGETKEKLYG QEMGSSEQVS ELLSEISRLS NTNERLEKLC RKLNKKLRSA
EKKANEFASQ AGHSGSPLFP SSPSIRSLDD PDDSISVSEN EPPPSYTPPS RSWFGLGGKN
QLSAKVEIDR QPKKASDGVL VFQARDLGSV VNAILESGNT IGNPRCGAAF LLFMALRHTD
ASNDDAMLKE LLIAIINGLK RMGKKHNRSL PAISQWTCVA IRFTHLIYQY SGEADSSLMN
DAQQNSHCLT NFDINEFRGF FSETATSLYK NTISLLQEKL KPLVVSAMLD HDSLHGNDAG
KSIEDLIREL GTSLDLIASF GADDVVIKQI CRQLIYYIVS IALNQLCARR DLCNWTKAMQ
LRYNVSQIEE YLSRRDMRDK NMLRELSPLV QASQLMQVKK QDEKDADNLL AMCESLTGAQ
VHKLLQLITP VHEYEERVPS KFLSIIKTKI SKNPGVIQRD LNYVAQPEFP YVPSSVKLNE
IDVPSEVRKH TQLV
//
