ID E4Y941_OIKDI Unreviewed; 826 AA.
AC E4Y941;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Transient receptor ion channel domain-containing protein {ECO:0000259|SMART:SM01420};
GN ORFNames=GSOID_T00029375001 {ECO:0000313|EMBL:CBY32078.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY32078.1};
RN [1] {ECO:0000313|EMBL:CBY32078.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FN654332; CBY32078.1; -; Genomic_DNA.
DR AlphaFoldDB; E4Y941; -.
DR Proteomes; UP000011014; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR NCBIfam; TIGR00870; trp; 1.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF54; TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF08344; TRP_2; 1.
DR PRINTS; PR01097; TRNSRECEPTRP.
DR SMART; SM00248; ANK; 2.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 523..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 608..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 221..283
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
FT REGION 728..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 769..788
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 826 AA; 94818 MW; D79785B29720E437 CRC64;
MPKVSGKINR ESLKITKLID QPRRSSMAAR NYSRRSSVIA AVDDSLGKTQ DAGELEDSDN
HNIIQLHQMR DPDEQHGSKE GEFLSIVSSG IASEVEDFLE NNEDFDTSCK DDLGRSALFI
AADANNMSMV QVLVKFEICM IDTLLFAIRK QNVSVVKMIL IEMKAQKKIC KHLSSNPGLV
ESEYDSEMTP IILAAHVNNY EILKLLLFEG TSLKRPHDVR CGCEVCISQM SKDSLRFSKS
RLNLYKALAC PYLIALSSEF PIRTAFKLSF ELRELSQVEN EFKSDYEALS VQCEIFAKEV
LDQTRSSKEL QTILNYSDET DALPNSGILS ALRLAVHFNQ KHFVAQPNCQ QLLSTLWYEG
VYGWRRMHWG LKLLYSLLIG LFWPILCMIH IIFPKSSAGQ LICRPFMKFI VGTASYLTFL
ALLVLASQVK VDHAGDDPGP PPSTIEWILL PWIISLIAAE IGQLWSGGAN DYVNDRWNVM
DFFMNSLYLA TISTKICAFL LHKDIPHHHR LSRVEWDPLH PTLISEALFS VANIFSFLRL
IYLFNSNVHM GPIQISLGRM LFDISKFLMI WFLVLFAFAN GLNQLYYKYG NAVCYGLMCE
KQNNAFSTLF HAMEALYWSA FGLVNLYVTD LEPEHFITKW VGATMFGIYN LINVIVLVNV
LIAMMNNSYQ FIADHADIEW KFARSKLWLT YFEESSPLPP PFNIIPTLEP IYDGIFLERT
FFRSTSRQVT REEIEEEQKP ADEAKEQPDK VQQIDEAFRK QVALNSELRK SQRLKDEENQ
RKIKDQQSEI KDLQFEMKDL QKIIKKINTE NKQLRNAHTR RGSFNY
//
