ID   E4YL80_OIKDI            Unreviewed;       759 AA.
AC   E4YL80;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSOID_T00028727001 {ECO:0000313|EMBL:CBY36241.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY36241.1};
RN   [1] {ECO:0000313|EMBL:CBY36241.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; FN654744; CBY36241.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4YL80; -.
DR   Proteomes; UP000011014; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.160.360; -; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR034732; EPHD.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR   Pfam; PF00856; SET; 1.
DR   Pfam; PF13832; zf-HC5HC2H_2; 1.
DR   SMART; SM00249; PHD; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS51805; EPHD; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          295..403
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51805"
FT   DOMAIN          617..744
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
SQ   SEQUENCE   759 AA;  84144 MW;  27009E73FFDAA4D3 CRC64;
     MGNIGSLEEI APRISHDFPV APASPEVHER GVFTFLDKEG IFDSLSVATK ERSCPSPELP
     MPSDTPRDPV TVTLTFRPDQ AGQPGDKSNI ENALKAISNI IGIKIEGYRV SQNGSPAQQH
     KTAVADAPIK EETRRCSKCG EHIIGEANKK PITSKQHPDS FYCTVSCRVI DQAFKEEASK
     LKISPSAADK TQKVHAYKRR NYRICLADLI DSDTSVFTDD LPDIAPQKIS SRGRRQTSET
     HLVNFGRPFL HKNVLWNVWN NKFASIPKIS TPDHGSNYRI LRLKYEQHFS KTTDKRSCLL
     CKTRGDGKAD TLGRLLNVGI SKWVHVNCIL WANDVREDSS GALINVNQGL SKCQPMSCAT
     CKGFGASVTC SRLRCDLAFH IECAFHSGGT FLRNRQFYCS AHLPKAYSSD TLQSLACCRR
     LFIDGCDIDA LYKPMCLSAP SVQLRVGSLK LFRLGVIDPA MQLLCDELKD FIAPIGLSWS
     RNFWTSPRER SSYKFCISRN GSSGRAEFKV QTTSASHSFN FDTQNNLSSI FDPIGLSFPK
     QAMTVAAFIL NFTAPQIQLL FQKMPLASYL GKNESTLGTS EKLAQALAPE AKRHCPANKL
     KHSSKTSQSH LNTPKQNTVY LQASPIHEIG LFSSKTLEPG HVIFELQTSN SKSVQSEEES
     FSIRFNESTA TKFIEDDSGP PCRYVNHSST PNCEFRLLDN NLPASELSLL TIASTNTSAK
     ASSKAALVSI KLVKKDEEIT VDYTRHSIAS RKHKLQLFS
//