ID E4ZH62_LEPMJ Unreviewed; 1229 AA.
AC E4ZH62;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 60.
DE SubName: Full=Similar to putative HOS3-like histone deacetylase {ECO:0000313|EMBL:CBX90632.1};
GN ORFNames=LEMA_P056660.1 {ECO:0000313|EMBL:CBX90632.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
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DR EMBL; FP929065; CBX90632.1; -; Genomic_DNA.
DR RefSeq; XP_003833997.1; XM_003833949.1.
DR AlphaFoldDB; E4ZH62; -.
DR STRING; 985895.E4ZH62; -.
DR EnsemblFungi; CBX90632; CBX90632; LEMA_P056660.1.
DR GeneID; 13285201; -.
DR eggNOG; KOG1343; Eukaryota.
DR HOGENOM; CLU_001880_0_1_1; -.
DR InParanoid; E4ZH62; -.
DR OMA; MTHGLTH; -.
DR OrthoDB; 10780at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR CDD; cd09998; HDAC_Hos3; 1.
DR Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR InterPro; IPR000286; His_deacetylse.
DR InterPro; IPR023801; His_deacetylse_dom.
DR InterPro; IPR037138; His_deacetylse_dom_sf.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR47558; HISTONE DEACETYLASE HOS3; 1.
DR PANTHER; PTHR47558:SF1; HISTONE DEACETYLASE HOS3; 1.
DR Pfam; PF00850; Hist_deacetyl; 1.
DR PRINTS; PR01270; HDASUPER.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002668}.
FT DOMAIN 275..612
FT /note="Histone deacetylase"
FT /evidence="ECO:0000259|Pfam:PF00850"
FT REGION 1..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 789..1060
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1087..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1192..1229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 693..723
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 758..772
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 805..825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 841..857
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..895
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 931..956
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1024..1056
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1229 AA; 132935 MW; 1E77E511F8DDF798 CRC64;
MQKYTHSSSS SPSSAARPGT PRRALQTNND ANQNQNQNQL SLSLSRKRLS LQAAAATNTG
LRSSPSPGLY SSPRHNLAES RRTPSSPNFQ GNPLSLSRSP SVASINRTSS PAMRRKSSTC
SLRGDNVNMT GSPRQPTSRR SSFHPHVPSP MGPNSPLHGG QQEKPPLRAC DVAEEHFKKE
LCRHEGVAGA VKAGTVVIVH DHCYGHRYSR PRTPKAMLNL IMERPERLLA SVLGIATAYV
RLGERHAQGS HPPHPHHNPP ERIPFKIRKT SRMVDINSQV VTNVHGTKWM AELKSLCDDA
GRKLASTGKE LAREGPVVPS GQASKKELHS GDLYLCPESL NAFQGALGGV LDAVDAVFQG
TSMGDGPSRA FVCIRPPGHH CSSDHPSGFC WLNNVHVGIE HAMMTYGLTH AAIIDFDLHH
GDGSQAITWA RNKKVQNMSK NTSNAKKTSI GYFSLHDINS YPCEDGDDDK VQAASLCIDN
AHGQSIWNVH LQSWRTVEEF WAIYEDKYMV LLDKTRQYLR HHTHRLHTTP NHPKPKAAIF
LSAGFDASEW ETAGMQRHSV NVPTEFYARF TRDVVRLAEE EGTGVEGRVI SVLEGGYSDR
ALTSGVLSHL SGLCDGQVFT ERKAEKGLAY EMRQRLGGLT LDDEDVPVQA NEDDSEPITY
DPLWWHASHL SELENLVSPS PVMPKKPRPE IHNHFSSPTQ SFAAKVVDPS KLNRSTSSRY
PSSPSRAPTP PPPDVDWATA AQALAKLLIP SDRQTRSFQP EDLAEPKVKK EKAAAPTLAS
VHVDLSGRQL RGRKAAPTYA DPDLDEVSVR GESRASRRKT IADFPIATED DPAPGRSAAS
RRMSIASSVS SIGDGNVSRA PSVAASRRSV APANSAGAKK TRGSSTATTR APQRPAAPSV
PSGHASKTKP VKGKENDGLD AITYGLKRVT LRMPSKEEYE AREKEKAAEA AKKAATKTTT
RKAAAVKPTV TKLTAKAATA KRAPGRPPKS AKAPSPVDAR PTTPMPASPE MQATEAGLVE
HSSHPMRRQS SSTVVAAQVM QDTQPRSRQS AVEGRTSASL MEAPRELGDA AMSPEQLREQ
LPMPSFVTVG EPVQNPSPSS RADTPPPPPP CSIPQFVNYT AHSFDEEVTA EGHYFANHHG
AESLQWLPPA TAASPSSATE CRPLSPACRK GSLPVFTAHG IIPFASSASR TQEAHAGLHS
AFGQQGAAPA VKHEDKSQDL WEVPDTPAR
//
