ID E4ZLX9_LEPMJ Unreviewed; 664 AA.
AC E4ZLX9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Purine transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=LEMA_P055150.1 {ECO:0000313|EMBL:CBX92809.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; FP929094; CBX92809.1; -; Genomic_DNA.
DR RefSeq; XP_003836174.1; XM_003836126.1.
DR AlphaFoldDB; E4ZLX9; -.
DR STRING; 985895.E4ZLX9; -.
DR EnsemblFungi; CBX92809; CBX92809; LEMA_P055150.1.
DR GeneID; 13285520; -.
DR eggNOG; ENOG502QQ5E; Eukaryota.
DR HOGENOM; CLU_024508_3_2_1; -.
DR InParanoid; E4ZLX9; -.
DR OMA; AYCTDAF; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF3; PURINE TRANSPORTER; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 105..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..450
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 664 AA; 72903 MW; 25DC9CB2F2511085 CRC64;
MSAIIRWAAS LNECVARSSF GRIFRLEGCE HDNEIKNAKF TTEVRAGLTT FFTMAYIIAV
NASILSDTGG NCVCNDPDDR YCLNDNKEYD ICVQNLHRDL ITATAAMAGL SSFLFGFLTN
MPVCLAPGMG LNAYFAYQVV GHHGRGPISY SLALTAVFLE GLIFIFLSLI GMRQWLVKVI
PSSLKIAAAC GIGLYLAEIG LSSASGIGAI SGAAQTPLTI AGCPDKYKNE MGECLSHKMT
SPTMWLGIMC GGVITAYLMM FKVRSAMIVA ILLVSVISWP RDTPVTYFPA TELGDHRWDF
FKQVVNFRPI RHTLNSLDWD LRKAPGHFAV ALFTFLYVDI IDCTATLYSM ARFCGVVDPE
TGDFPRSTLA YCTDATCISI GALLGTSPVT VFVESGAGIA EGGKTGLTAI TCGTCFIISM
FFAPIFASIP PWATGCTLIL VGCLMMRQIV SVNWRYIGDA VPAFVTVMFI PFGYSAAYGL
IAGMMIYTAL NGLVYITKIV SGGYIVPEDE DHREYWTITP HGRRPWFVGA SVWLADRLNH
NAKREKDDNA SIRSSGSRWE NQGRIASYGS SRELQAITTH PLLTDPRQEK VLRKICRQKY
TDTQAWLKVS QSVPPAHDGI PFEACRTPHQ ARRTSPMKRQ INATHYVVGR SPAFRASLQL
SIQD
//
