ID E4ZM58_LEPMJ Unreviewed; 953 AA.
AC E4ZM58;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=LEMA_P051130.1 {ECO:0000313|EMBL:CBX92407.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
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DR EMBL; FP929094; CBX92407.1; -; Genomic_DNA.
DR RefSeq; XP_003835772.1; XM_003835724.1.
DR AlphaFoldDB; E4ZM58; -.
DR STRING; 985895.E4ZM58; -.
DR EnsemblFungi; CBX92407; CBX92407; LEMA_P051130.1.
DR GeneID; 13287136; -.
DR eggNOG; KOG0221; Eukaryota.
DR HOGENOM; CLU_002472_8_0_1; -.
DR InParanoid; E4ZM58; -.
DR OMA; METHQDG; -.
DR OrthoDB; 9867at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03281; ABC_MSH5_euk; 1.
DR Gene3D; 1.10.1420.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF00488; MutS_V; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668}.
FT DOMAIN 781..797
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..86
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 953 AA; 105260 MW; B80D8C131F3963BE CRC64;
MPPRKPPHKP SFRYRSRRSI ASAHNSGGGT SLDTSGSSTS RRSSVHSPSA ATVVLNRSHR
PARRGSFLED ESTHVPSQNG REDDDTLNEV IMAVDLLPRG VVGCSYYVAR DEKMFFMEDI
PFGNVDIIDT LRLSIEPTVI LVSTKIDDSV INRFDPEGRN DDSASVDNDQ FRLPFLLEVR
PPSEFYYDAA KSKLQSLQLE GTEVSQISFN VSSELPAAHQ FNDGDTFGQQ GQLLRLAGLI
DLESRVTVGC AGALISYLQR RRAAAYLPGD HSAYLMFRVT TLGMFSLRDT MFINADTLHS
LQILDAESHP HSHNRGPTKS SSGAKEGLSV YGLFHRLART SQGRTLLRQY FLRPSLNIDM
INERLHTVGV LVRPENESAL QDLGQNLKNI GNMRIVLMNL KKGVSGSTQS RSGLSRTVWV
AIRTFSFFAL KIKDALQDVL GEDHLPIRDK VFENFESYHL AQIGRKLSET IDLDRSAEES
RTVILTGVDE ELDQMKRTLD GLGSLLNEVA AKLSEMMPSD LRAALNVIYF PQIGFLVTVP
IDPTTGSEVY DGGFESQWER MFATEDQVYF KSSETREMDD HFGDVYGIIS DREIEISHEL
AQHVLQYEEL ITTCSDICGE LDSLVALAQG AKQYRLCRPR VTHDNVLQIK GGRESHILQE
LTVSSFVPND TLLVGGIGRD ARSGHDTDIP RLTGSTHELP SMLVLTGPNY SGKSVYLKQV
ALIVFMAHVG CFVPADSADI GLTDKILSRV TTRETVSRAQ SAFMIDLQQI SLALSLATRR
SLLIIDEFGK GTESSDGAGL ACAVMEHLLS LGPERPKVIG ATHFHEIFEL GHLDPRPSLA
FGHMEVRIDT DASEVNDQIT YLYKNGRSTS SFGTCCADIN GVPPEIIQRA ENLILLSMRG
EDLVAACCQM PADEVAELEE AEQIAREFLE ADVYKNPNAT LAGIFTTSTT SDS
//
