ID E4ZUJ7_LEPMJ Unreviewed; 1099 AA.
AC E4ZUJ7;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Similar to ATP-binding cassette sub-family G member 2 {ECO:0000313|EMBL:CBX95076.1};
GN ORFNames=LEMA_P114910.1 {ECO:0000313|EMBL:CBX95076.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC Eye pigment precursor importer (TC 3.A.1.204) subfamily.
CC {ECO:0000256|ARBA:ARBA00005814}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; FP929126; CBX95076.1; -; Genomic_DNA.
DR RefSeq; XP_003838555.1; XM_003838507.1.
DR AlphaFoldDB; E4ZUJ7; -.
DR STRING; 985895.E4ZUJ7; -.
DR EnsemblFungi; CBX95076; CBX95076; LEMA_P114910.1.
DR GeneID; 13288173; -.
DR eggNOG; KOG0061; Eukaryota.
DR HOGENOM; CLU_000604_57_1_1; -.
DR InParanoid; E4ZUJ7; -.
DR OMA; NCQLDAF; -.
DR OrthoDB; 359054at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03213; ABCG_EPDR; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48041; ABC TRANSPORTER G FAMILY MEMBER 28; 1.
DR PANTHER; PTHR48041:SF139; PROTEIN SCARLET; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:CBX95076.1};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..1099
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003194543"
FT TRANSMEM 318..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 844..866
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 878..900
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..945
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 957..980
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 987..1007
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1074..1096
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 82..121
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 374..615
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 667..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 667..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 111..120
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1099 AA; 120969 MW; C0B95A1B019498BF CRC64;
MRQTAWAASL LALISLTGSS AAHKTLANYS LPDSQASLFS LYDDRPDGCP PCFNCNLDDF
KCHQFADCSK ANGRCNCPPG FGGVDCSEPL CGSLADGKDR APRGGEAECQ CKEGWTGINC
NVCETNQACN ALMPEGEGGV CYKDGQLVKE NYQICDITNR KILDQLKEKK PQATFSCNAE
SEECNFQFWV AQRESFYCSL DTCTSQFTAE SDRNITKYRC ENIKCECVPD RMLCGEDGSV
DIGDFLKESI KGPAEFRSIA STNSKESGSV FSEPAMNDLI QSIFGDESIF LQCDTGECLY
HTEVPGYERP VKKINTPLIA GVIAGCALFI VAAILGIWYL THRNEYQRYG AIHLSDDEED
ENAKLLADHK PAALLFENVA YNLNGKQILT GISGAVHPGE LLAIMGASGA GKTTFLDILA
RKNKIGATSG DFYLNGEKIR DDEFRGVIGF VDQEDTLLPT LTVHETILDS ALLRLPKEMS
RMSKEQKVED VERQLGIYHI RNQKIGSEES GRGISGGEKR RVGIACELVT SPSILFLDEP
TSGLDAFNAF NVVECLVNLV KNYNRTVVFT IHQPRSNIVA LFDQLILLAK GRAVYSGPFE
NCQAYFDDIG YTCPPGFNIA DYIVDLTMHA SAARHTIDED SSLFNREGLH TSASSAIAVK
SIPSINTSEF DRDVPGSPSN SSIRPKGKRR TSIKQQQERE LFTRKKTASL QNGTMSPKTD
DEVPYDRRGA IKAQWLKLTR QQGGVPPQIL EDPDEYPPPA NGSTGTNLDI LINAYNASDI
AASLREDIAS AVASANQANG TNGVSDLNGF VAAGKLKGFR KVGFFGQFSI LSRRTWRNLY
RNPMLMLTHY AIAIVLAVFL GFLFYGLTDD IKGFQNRLGL FLFVLSLFGF SSLTILTVFA
PERLLFTRER AKGYYSPPSY FLAKVLFDII PLRLLPPLIL GIIVYPMTGL IPAWANFLKF
ELFLTLFNLA AAAIFLFIGI VFRNSGVANL IGVLVMLFSL LFSGFFLNKE SIPAIAKWLQ
SLSIFHYAFE GLIVNEVKYL SLIDHKYGLD IEVPGSAILS SFGFNTAALW TDCIGLAVFG
SAFVVLAYLA MHLLLVERR
//
