ID E5A8X9_LEPMJ Unreviewed; 532 AA.
AC E5A8X9;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Similar to cytochrome P450 monooxygenase {ECO:0000313|EMBL:CBY00074.1};
GN ORFNames=LEMA_P076630.1 {ECO:0000313|EMBL:CBY00074.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971};
CC -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC {ECO:0000256|ARBA:ARBA00010617}.
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DR EMBL; FP929137; CBY00074.1; -; Genomic_DNA.
DR RefSeq; XP_003843553.1; XM_003843505.1.
DR AlphaFoldDB; E5A8X9; -.
DR STRING; 985895.E5A8X9; -.
DR EnsemblFungi; CBY00074; CBY00074; LEMA_P076630.1.
DR GeneID; 13289351; -.
DR eggNOG; KOG0158; Eukaryota.
DR HOGENOM; CLU_001570_14_0_1; -.
DR InParanoid; E5A8X9; -.
DR OMA; WYYHAAR; -.
DR OrthoDB; 1202047at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR CDD; cd11060; CYP57A1-like; 1.
DR Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR InterPro; IPR001128; Cyt_P450.
DR InterPro; IPR002401; Cyt_P450_E_grp-I.
DR InterPro; IPR036396; Cyt_P450_sf.
DR PANTHER; PTHR24305; CYTOCHROME P450; 1.
DR PANTHER; PTHR24305:SF77; CYTOCHROME P450 MONOOXYGENASE; 1.
DR Pfam; PF00067; p450; 1.
DR PRINTS; PR00463; EP450I.
DR PRINTS; PR00385; P450.
DR SUPFAM; SSF48264; Cytochrome P450; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000313|EMBL:CBY00074.1};
KW Oxidoreductase {ECO:0000313|EMBL:CBY00074.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 532 AA; 59892 MW; 232A52C5880286BF CRC64;
MSFLTGVPFQ LFPVLFLLLA IYLVSGRARE YWRLRHFKGP RTAGISWIRH SKAVASGKSY
EYYGDVCEKY GPIARIAPNH LVTSDPDVWA KINAVRSPYS RAPWFYHTAR FESGKDNVFT
DCDNDRHDVR RKKMAAGYSG KENPTLEPSI DEHVEELIAL VRKYASTKNT TVPSTPMDLA
KKIPFFTLDV ISHIGLGEPF GDLRADEDIK DYLKSSEEGL RIGNTALALG IAWLKDMPII
GPAISPSEKD TFGFGRMMTE ARKIVNQRRL KSTSEKSDML ASFARNGVAG DDLCKFPSPP
RTKTSSNLHN LVQEAFEQII AGSDTTAAAI RIILLYLMTH PRVYTKLQSE IDHTVESDIA
GPNTVSDKAA RQLPYLGAVV REALRVHPPV VNLFSRVTPP EGDIFTINGT ETHIPGGTLI
GYSAWAMHRN NRALYGEDAH VFRPERWFLD SSTAENRDRL ARMTKTNDMI FGHGRWVCLG
RNIALIEIHK CIFELLRHFD LALTDPAAPW KTFNSLGLWE IRDMWVDVTA RD
//
