ID   E5CYU7_CHLTH            Unreviewed;       742 AA.
AC   E5CYU7;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Penicillin binding protein {ECO:0000313|EMBL:ADJ67954.1};
DE   Flags: Fragment;
GN   Name=pbpB {ECO:0000313|EMBL:ADJ67954.1};
OS   Chlamydia trachomatis.
OC   Bacteria; Chlamydiota; Chlamydiia; Chlamydiales; Chlamydiaceae;
OC   Chlamydia/Chlamydophila group; Chlamydia.
OX   NCBI_TaxID=813 {ECO:0000313|EMBL:ADJ67954.1};
RN   [1] {ECO:0000313|EMBL:ADJ67954.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PbpB_40 {ECO:0000313|EMBL:ADJ67954.1};
RA   Herrmann B., Klint M., Christerson L.;
RT   "Multi locus sequence typing (MLST) of Chlamydia trachomatis.";
RL   Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
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DR   EMBL; GQ352807; ADJ67954.1; -; Genomic_DNA.
DR   AlphaFoldDB; E5CYU7; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT   DOMAIN          24..252
FT                   /note="Penicillin-binding protein dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF03717"
FT   DOMAIN          312..345
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADJ67954.1"
FT   NON_TER         742
FT                   /evidence="ECO:0000313|EMBL:ADJ67954.1"
SQ   SEQUENCE   742 AA;  86356 MW;  2A42924F213E5D93 CRC64;
     VQHEKKKEEA YRPQRRSVPE HCDRAGVCDR FGKTLAENVL QYNVGISYRA IRDIPTRIWH
     TDEQGNKRLV PVRKDYIKKF ADFLAQELHM DRDFVEDTIH AKASVLGSVP YILQANVSER
     TFLRLKMLEK DWPGLHVESS VRRHYPEGRA VADLLGYVGP ISAEEHRKIT RELGNLRECI
     RAYEEGEDPK FPAGISSVDQ VRKLLHELEM HAYGLNSLIG KLGVEAFCDR KLRGLIGKRS
     MLVDRRGNFI QEMEGSSVGS PGRKIQLTIS TELQAFAHEL LAEHERGEVF RDYRQWRQQQ
     YLPPFFPWIK GGAIVAMDPK NGQILAMASS PRYDNNDFIN MKDSPNQEEC RSSVLRWLEN
     LEYIGEVFDR RVPLRRERLD PLSGKYFDEE LSFSYRAFLD FILPDTSKVK QMLCEKGSVG
     LSIYLQGTIE QLLEMFECEE KECGLVFDVL FPKEDGHEII GEVTSLKRQK QFKAILAERE
     EEVQAFRDRL GSIFADLSAN YDKILFLDLL RTAVDPEKVS ISLLAEIGHM SVLDFVDYQG
     HFIALRKSFA KLMENAFIDH DFTAWREEHF TQFIKQKRDE ELERKQRYPT PYVDYLVEER
     SRQYALFCRE HMDSFITFLL SEIEPPLGNP YYQEIACWRQ ELRSGAYPAL EWREHYDFLH
     KHLSQTSYDL CELFAAFREF SELKRPLYGQ YPLTLTRNIE QIEQDLIASF YPLYGYGHLS
     AHAFGQAATL GSIFKLVSAY SV
//