ID   E5VJ62_9FIRM            Unreviewed;       393 AA.
AC   E5VJ62;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:EFV17137.1};
GN   ORFNames=HMPREF0996_01073 {ECO:0000313|EMBL:EFV17137.1};
OS   Lachnospiraceae bacterium 5_1_63FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658089 {ECO:0000313|EMBL:EFV17137.1, ECO:0000313|Proteomes:UP000005278};
RN   [1] {ECO:0000313|EMBL:EFV17137.1, ECO:0000313|Proteomes:UP000005278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5_1_63FAA {ECO:0000313|EMBL:EFV17137.1,
RC   ECO:0000313|Proteomes:UP000005278};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA   Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA   Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA   Allen-Vercoe E., Ambrose C., Strauss J., Daigneault M., Haas B.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium strain 5_1_63FAA.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFV17137.1}.
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DR   EMBL; ACTS01000021; EFV17137.1; -; Genomic_DNA.
DR   AlphaFoldDB; E5VJ62; -.
DR   HOGENOM; CLU_007207_0_4_9; -.
DR   Proteomes; UP000005278; Unassembled WGS sequence.
DR   GO; GO:1990362; F:butanol dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd08187; BDH; 1.
DR   Gene3D; 3.40.50.1970; -; 1.
DR   Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 1.
DR   InterPro; IPR001670; ADH_Fe/GldA.
DR   InterPro; IPR018211; ADH_Fe_CS.
DR   InterPro; IPR044731; BDH-like.
DR   PANTHER; PTHR43633; ALCOHOL DEHYDROGENASE YQHD; 1.
DR   PANTHER; PTHR43633:SF1; ALCOHOL DEHYDROGENASE YQHD; 1.
DR   Pfam; PF00465; Fe-ADH; 1.
DR   SUPFAM; SSF56796; Dehydroquinate synthase-like; 1.
DR   PROSITE; PS00060; ADH_IRON_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          9..382
FT                   /note="Alcohol dehydrogenase iron-type/glycerol
FT                   dehydrogenase GldA"
FT                   /evidence="ECO:0000259|Pfam:PF00465"
SQ   SEQUENCE   393 AA;  43393 MW;  15D063EFE817390A CRC64;
     MLNFQYFTPT KVVFGKDAEL KVGPLVKEEG CKKVLVHYGG QSAKKSGLLD RVCEALKDFD
     IDYVTLGGVV PNPHLSKVYE GIELCKKEGV DFILAVGGGS VIDSCKAIAY GLGNPEVDVW
     DLFTGKARPK ACYPLGSVLT IAAAGSEMSN SCVITNEEGW YKKALDTDLA RPKFAIMNPE
     ITYTLPDYQT QCGCADIMMH TMERYFVLED TMEITDKIAQ DVMKNVMKYA KILKKDPENY
     EARAEIMWCG SLSHNGLTGC GTCGGDWATH LIEHELGGMF DVAHGAGLAA VWGSWARYVM
     DEKPERFAQF AVDVMGVEES DDVKSTALKG IEAVEEFYRM IEMPTNMKEL GINPTDEQIK
     DMAMKATNHD TQQLGAFKKL SAKDLVEIYK TAK
//