ID   E5VNG8_9FIRM            Unreviewed;       297 AA.
AC   E5VNG8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Aldo/keto reductase {ECO:0000313|EMBL:EFV15600.1};
GN   ORFNames=HMPREF0996_02582 {ECO:0000313|EMBL:EFV15600.1};
OS   Lachnospiraceae bacterium 5_1_63FAA.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=658089 {ECO:0000313|EMBL:EFV15600.1, ECO:0000313|Proteomes:UP000005278};
RN   [1] {ECO:0000313|EMBL:EFV15600.1, ECO:0000313|Proteomes:UP000005278}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5_1_63FAA {ECO:0000313|EMBL:EFV15600.1,
RC   ECO:0000313|Proteomes:UP000005278};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA   Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA   Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA   Allen-Vercoe E., Ambrose C., Strauss J., Daigneault M., Haas B.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lachnospiraceae bacterium strain 5_1_63FAA.";
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFV15600.1}.
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DR   EMBL; ACTS01000063; EFV15600.1; -; Genomic_DNA.
DR   AlphaFoldDB; E5VNG8; -.
DR   HOGENOM; CLU_023205_8_0_9; -.
DR   Proteomes; UP000005278; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd19092; AKR_BsYcsN_EcYdhF-like; 1.
DR   Gene3D; 3.20.20.100; NADP-dependent oxidoreductase domain; 1.
DR   InterPro; IPR020471; AKR.
DR   InterPro; IPR018170; Aldo/ket_reductase_CS.
DR   InterPro; IPR023210; NADP_OxRdtase_dom.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   PANTHER; PTHR43364; NADH-SPECIFIC METHYLGLYOXAL REDUCTASE-RELATED; 1.
DR   PANTHER; PTHR43364:SF1; OXIDOREDUCTASE YDHF; 1.
DR   Pfam; PF00248; Aldo_ket_red; 1.
DR   PRINTS; PR00069; ALDKETRDTASE.
DR   SUPFAM; SSF51430; NAD(P)-linked oxidoreductase; 1.
DR   PROSITE; PS00062; ALDOKETO_REDUCTASE_2; 1.
PE   4: Predicted;
FT   DOMAIN          15..288
FT                   /note="NADP-dependent oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00248"
SQ   SEQUENCE   297 AA;  34255 MW;  3F9C0E35787B848B CRC64;
     MTKIKLTDNL SLSQIIRGFW RLDTWELSTD ELIDNMKSSI DLGVTSFDTA EIYADTLCES
     QIGEAFAKDP ALRGKVELIS KTGIYKQEIN GESFGYYNTT YDRIVRSCKE SLQRLHTDYL
     DLYLIHREDP LLDPWEAGRA MLDLKKEGLI KEIGVSNFDP FKFDAMNKAV DGALVTNQIE
     WNPVCFEHFN SGMMDYLTVN KIHPMIWSPL AGGRLFQEDD LQCKKAMDKI KEIAERHNCE
     PDTIVYAWIM YHPVQAMPIV GSRKVERIES AVKAMDVKLE HYEWYEIYAA SGQQQIR
//