ID E5WGB1_9BACI Unreviewed; 504 AA.
AC E5WGB1;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Xylulose kinase {ECO:0000256|RuleBase:RU364073};
DE Short=Xylulokinase {ECO:0000256|RuleBase:RU364073};
DE EC=2.7.1.17 {ECO:0000256|RuleBase:RU364073};
GN Name=xylB {ECO:0000256|RuleBase:RU364073};
GN ORFNames=HMPREF1013_01486 {ECO:0000313|EMBL:EFV78298.1};
OS Bacillus sp. 2_A_57_CT2.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=665959 {ECO:0000313|EMBL:EFV78298.1, ECO:0000313|Proteomes:UP000003283};
RN [1] {ECO:0000313|EMBL:EFV78298.1, ECO:0000313|Proteomes:UP000003283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2_A_57_CT2 {ECO:0000313|EMBL:EFV78298.1,
RC ECO:0000313|Proteomes:UP000003283};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Strauss J.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D., Howarth C.,
RA Larson L., Lui A., MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C.,
RA Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., White J., Yandava C., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacillus sp. strain 2_A_57_CT2.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+);
CC Xref=Rhea:RHEA:10964, ChEBI:CHEBI:15378, ChEBI:CHEBI:17140,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:57737, ChEBI:CHEBI:456216;
CC EC=2.7.1.17; Evidence={ECO:0000256|RuleBase:RU364073};
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|RuleBase:RU364073}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV78298.1}.
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DR EMBL; ACWD01000021; EFV78298.1; -; Genomic_DNA.
DR RefSeq; WP_009332079.1; NZ_GL635751.1.
DR AlphaFoldDB; E5WGB1; -.
DR eggNOG; COG1070; Bacteria.
DR HOGENOM; CLU_009281_3_0_9; -.
DR Proteomes; UP000003283; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004856; F:xylulokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0005997; P:xylulose metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR006000; Xylulokinase.
DR NCBIfam; TIGR01312; XylB; 1.
DR PANTHER; PTHR43095; SUGAR KINASE; 1.
DR PANTHER; PTHR43095:SF5; XYLULOSE KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU364073};
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU364073};
KW Kinase {ECO:0000256|RuleBase:RU364073};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU364073};
KW Reference proteome {ECO:0000313|Proteomes:UP000003283};
KW Transferase {ECO:0000256|RuleBase:RU364073};
KW Xylose metabolism {ECO:0000256|RuleBase:RU364073}.
FT DOMAIN 5..247
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 283..446
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 504 AA; 56723 MW; 4DB28BD8B34A6502 CRC64;
MNEQYVLGID HGSGGCKVTC LKSDGTISSE AYVPYPSFYP HPKWVEQEPE MWIEAAFEAV
SKATEKLGPY GRKNIKALSF TAPHHVAVLL DKDRQVIRPA IMWNDQRSGE QSKQLSELYG
KKIFELTYNA PNPTWTLSHL LWLKQHEPEQ YGKIDKILFM KDYVRYRFSS QMATDYIEAE
GTLLYDIEKQ EWSDFLLSLI DLDESAFPPV LSPTEVCGTI SPDIAKCLGL SEKTRIIIGT
ADTAAEVYGC GTIKGGDGVV KLATAGNFCL VTDTVTKNEK LTTYHHLVDN LFYQNSATNF
AAASFRWFKE SFFQEFEESM KVPSIYPEIM KQVELIKPGS EGLIFHPYLN GERSPHWDPY
LRGSFFGCTA RHSRSHFARA VLEGVGFSLK DCSLQFPNKH LKKIRIIGGG SKGREWVQII
ADILNVELEV PASSDASFGA ALVAATGIGW FADLKEAAQS TESVIYSLEP KEKNIGGYEE
LFSIYQELHS RTYELSHRLS QFSF
//
