ID   E6BFK6_ECOLX            Unreviewed;       226 AA.
AC   E6BFK6;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=NAD dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:EFU37046.1};
GN   ORFNames=HMPREF9350_01108 {ECO:0000313|EMBL:EFU37046.1};
OS   Escherichia coli MS 85-1.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=679202 {ECO:0000313|EMBL:EFU37046.1, ECO:0000313|Proteomes:UP000005056};
RN   [1] {ECO:0000313|EMBL:EFU37046.1, ECO:0000313|Proteomes:UP000005056}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MS 85-1 {ECO:0000313|EMBL:EFU37046.1,
RC   ECO:0000313|Proteomes:UP000005056};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFU37046.1}.
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DR   EMBL; ADWQ01000003; EFU37046.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6BFK6; -.
DR   PATRIC; fig|679202.3.peg.1034; -.
DR   Proteomes; UP000005056; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000534; Semialdehyde_DH_NAD-bd.
DR   PANTHER; PTHR14097; OXIDOREDUCTASE HTATIP2; 1.
DR   PANTHER; PTHR14097:SF7; OXIDOREDUCTASE HTATIP2; 1.
DR   Pfam; PF13460; NAD_binding_10; 1.
DR   SMART; SM00859; Semialdhyde_dh; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          18..118
FT                   /note="Semialdehyde dehydrogenase NAD-binding"
FT                   /evidence="ECO:0000259|SMART:SM00859"
SQ   SEQUENCE   226 AA;  24819 MW;  B2B326893190E7A1 CRC64;
     MSRGAQGRQF CKGAKMSQVL ITGATGLVGG HLLRMLINEP KVNAIAAPTR RPLGDMPGVF
     NPHDPQLTDA LAQVTDPIDI VFCCLGTTRR EAGSKEAFIH ADYTLVVDTA LTGRRLGAQH
     MLVVSAMGAN AHSPFFYNRV KGEMEEALIA QNWPKLTIAR PSMLLGDRSK QRMNETLFAP
     LFRLLPGNWK SIDARDVARV MLAESMRPEH EGVTILSSSE LRKRAE
//