ID E6K466_9BACT Unreviewed; 729 AA.
AC E6K466;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Glutamate--ammonia ligase, catalytic domain protein {ECO:0000313|EMBL:EFU31615.1};
DE EC=6.3.1.2 {ECO:0000313|EMBL:EFU31615.1};
GN Name=glnA {ECO:0000313|EMBL:EFU31615.1};
GN ORFNames=HMPREF6485_0389 {ECO:0000313|EMBL:EFU31615.1};
OS Segatella buccae ATCC 33574.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Segatella.
OX NCBI_TaxID=873513 {ECO:0000313|EMBL:EFU31615.1, ECO:0000313|Proteomes:UP000003112};
RN [1] {ECO:0000313|EMBL:EFU31615.1, ECO:0000313|Proteomes:UP000003112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33574 {ECO:0000313|EMBL:EFU31615.1,
RC ECO:0000313|Proteomes:UP000003112};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutamine synthetase family.
CC {ECO:0000256|PROSITE-ProRule:PRU01330, ECO:0000256|RuleBase:RU000384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU31615.1}.
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DR EMBL; AEPD01000010; EFU31615.1; -; Genomic_DNA.
DR RefSeq; WP_004341525.1; NZ_GL586311.1.
DR AlphaFoldDB; E6K466; -.
DR STRING; 873513.HMPREF6485_0389; -.
DR eggNOG; COG3968; Bacteria.
DR HOGENOM; CLU_024307_0_0_10; -.
DR Proteomes; UP000003112; Unassembled WGS sequence.
DR GO; GO:0004356; F:glutamine synthetase activity; IEA:UniProtKB-EC.
DR GO; GO:0006542; P:glutamine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.20.120.1560; -; 1.
DR Gene3D; 3.30.590.10; Glutamine synthetase/guanido kinase, catalytic domain; 1.
DR InterPro; IPR040577; Gln-synt_C.
DR InterPro; IPR008147; Gln_synt_N.
DR InterPro; IPR014746; Gln_synth/guanido_kin_cat_dom.
DR InterPro; IPR008146; Gln_synth_cat_dom.
DR InterPro; IPR027303; Gln_synth_gly_rich_site.
DR InterPro; IPR022147; GSIII_N.
DR PANTHER; PTHR42974; GLUTAMINE SYNTHETASE; 1.
DR PANTHER; PTHR42974:SF1; TYPE-3 GLUTAMINE SYNTHETASE; 1.
DR Pfam; PF00120; Gln-synt_C; 1.
DR Pfam; PF18318; Gln-synt_C-ter; 1.
DR Pfam; PF12437; GSIII_N; 1.
DR SMART; SM01230; Gln-synt_C; 1.
DR SUPFAM; SSF55931; Glutamine synthetase/guanido kinase; 1.
DR PROSITE; PS00181; GLNA_ATP; 1.
DR PROSITE; PS51986; GS_BETA_GRASP; 1.
DR PROSITE; PS51987; GS_CATALYTIC; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:EFU31615.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000003112}.
FT DOMAIN 85..174
FT /note="GS beta-grasp"
FT /evidence="ECO:0000259|PROSITE:PS51986"
FT DOMAIN 179..615
FT /note="GS catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51987"
SQ SEQUENCE 729 AA; 82814 MW; 75FAE196337D9916 CRC64;
MANLRFEVVA EAFRKRPLEV EVPKERPSEF FGKYVFNRSK MYKYLPADVY EKLVDVMDNG
TRLDRSIADA VAAGMKQWAE ENGVTHYTHW FQPLTEGTAE KHDAFVEHDG KGGMIEDFSG
KLLVQQEPDA SSFPNGGIRN TFEARGYSAW DPTSPVFIID DTLCIPTIFI SYTGEALDYK
APLLRSLHAV NVAATEVCHY FDKNVKKVQT NLGWEQEYFL VDESLYSARP DLMLTGRTLM
GHDSAKNQQM DDHYFGTIPE RVQAFMKDLE IQALELGIPC KTRHNEVAPN QFELAPIYEE
CNLAVDHNML LMSLMKKVAH RHSFRVLLHE KPFDGVNGSG KHNNWSLTTD TGVLLHAAGK
TPEANLRFVV FIVETLMAVY RHNGLLKASV MSATNDHRLG ANEAPPAIIS SFLGKQLTDL
LNHIEKADKD ELFTVAGKKG MELDIPEIPE LMIDNTDRNR TSPFAFTGNR FEFRAVGSEA
NCASALIVLN SAMAEALTDF KRRVDALIAG GEDRTSAIID IIREDIKTCR PIRFDGNGYS
DEWKAEARER GLDCEASCPV CFDRYLDAES IRMFESTGVM KENELRARNE VKWETYTKKI
QIEARVMGDL TMNHVIPVAT HYQSRLAKNV EGMFNIFGRE EGARLTARNV KIIREIAERT
EKIETGVEEL VNARKKANRI ESEREKAVAY HDIVAPKMEE IRYQIDKLEL MVADELWTLP
KYRELLFIR
//
