ID E6KNN7_STROR Unreviewed; 2172 AA.
AC E6KNN7;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Gram-positive signal peptide protein, YSIRK family {ECO:0000313|EMBL:EFU62301.1};
GN ORFNames=HMPREF8578_1852 {ECO:0000313|EMBL:EFU62301.1};
OS Streptococcus oralis ATCC 49296.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888049 {ECO:0000313|EMBL:EFU62301.1, ECO:0000313|Proteomes:UP000004500};
RN [1] {ECO:0000313|EMBL:EFU62301.1, ECO:0000313|Proteomes:UP000004500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49296 {ECO:0000313|EMBL:EFU62301.1,
RC ECO:0000313|Proteomes:UP000004500};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU62301.1}.
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DR EMBL; AEPO01000016; EFU62301.1; -; Genomic_DNA.
DR eggNOG; COG1196; Bacteria.
DR eggNOG; COG3583; Bacteria.
DR HOGENOM; CLU_000802_1_0_9; -.
DR Proteomes; UP000004500; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.160.20.110; -; 1.
DR Gene3D; 1.20.120.1850; Ebh helix bundles repeating unit (S and A modules); 2.
DR Gene3D; 2.20.230.10; Resuscitation-promoting factor rpfb; 4.
DR InterPro; IPR011098; G5_dom.
DR InterPro; IPR011493; GLUG.
DR InterPro; IPR009063; Ig/albumin-bd_sf.
DR InterPro; IPR011505; Peptidase_M26_C_dom.
DR InterPro; IPR008006; Peptidase_M26_N_dom.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF07554; FIVAR; 2.
DR Pfam; PF07501; G5; 4.
DR Pfam; PF07581; Glug; 1.
DR Pfam; PF07580; Peptidase_M26_C; 1.
DR Pfam; PF05342; Peptidase_M26_N; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR SMART; SM01208; G5; 4.
DR SUPFAM; SSF46997; Bacterial immunoglobulin/albumin-binding domains; 1.
DR PROSITE; PS51109; G5; 4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 273..353
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 379..459
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 474..554
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT DOMAIN 569..649
FT /note="G5"
FT /evidence="ECO:0000259|PROSITE:PS51109"
FT REGION 230..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2172 AA; 241481 MW; B6AB254CB1A0138A CRC64;
MWLLFIANKL NNLVNFGRIE GIQIMIKERL GMKRSYLGEK HQRFSLRKVS VGLVSALVGV
FYLFSGGGSL VSVAASEQTP SVTKQVHYKY VTESELTDQE KQLVVKELPQ FAEETDDTYY
LIYRPTRQLP ATGHSQLISS IAAGAGIVLL VVAIKLGRDD RKKLASFMLL TSLGSQLIAP
TSLALTNQML ADYNQELTVQ VGEALQSPLT IEGYQYVGYL KSQKAVNSPV DGKKELNHST
PIDTPVQTSN GSQAQEEYRF QKPSDAPVFE QPELKVESKD TSRTEIIPFQ VEEEEAADLP
QGQTEVIQAG KNGSRTIVTR SYILNGQVIH TEEVSNQVTT EPTSEIRKVG SKVLSPTKPS
PEESVSEKPT DAPINEVPSL NVEEKDVTTT VAEPYTRERV ESDSLPVGQT KITQAGQDGV
RTIVTRQYMV DGKVERSQEL SNEVTTPAVS EIVTVGTGPV SEKPTDAPIN EVPSLNVEEK
DVTTTIAEPY TRERVESDSL PFGQTKITQA GQDGVRTIVT RQYIVDGKVE RSQEISNEVT
TPAVSEIVTV GTAPVSEKPT DAPVNEVPSL NVEEKDVTTT VAESYPTKEV ESADLPLGQR
EVSQAGQDGV RTIVTRQYLV DGKVENTEEI SNTITKEAVP QIIKVGTKPI STNADHAPVE
PEKGTLDLEP LHQLVEEADS IQKTHQYFND TTADQESYKQ AVANAQALFE ASHASQEQVD
SLKKALETAK NNLDGQPVDK KTLGVEFDMK DVTQSTVAYQ YADEQAKLRY RRALDQAKLV
LDNPLANQAL VDQVRTDLEA ARQALDGVKR KPTLSLVRVE KEEDQRQVSL SYHLTDATAS
YQSAKVQLYK GQTLIKEVDL VDLSKQLTLD DLDYYTPYTL KTVMKYDLGQ GEQTSIEDQR
PVQLDYKKVE IKDIDRIELY GKDGSHYRRY LSLSEVPSDL NNYYVRIQSD KFKDMLLPVS
KITDKGNAYS VTVSANQLVE GEGDHYRPDY SFELPKTPLS QEGVYTSFKA LIEAMKSNPT
GNFKLGADVS ADEVELEHSA TSYVPEEFSG SLTSRVDGKD YTIYNLAKPL FATLKNATIQ
QLTLKSAAVT GKDSIGALAS NAQNATITDV SVSGSLSGNK HIGGLVGVAQ NTKLTNVTFK
GSITSTQDGG QEYNIGGLVG NFHGNQSLAQ KSQADVSIQV TGRNGDQRVG GLIGRLQNGA
RLETSYVTGS IQNAGHSGQV GGAIGSTWNN GQVRNILTSV KVQNGHAMTG DPYPEASVRD
SYVLEGTTAN RKDERFVRSI SEADAQAKRQ SFGITSNLTD QEPLQQAYQH QTDYSRVRGA
QESRKQAYEN VEKLLPFYNK DFIVHTANQL AEDDKLNKVA LLDVVPMKDE TLITDVNSYK
GEINRLMLHY ADKTIAYLDL AYKGDFANGQ IAEYSIADKN LLYTPEAFLS DYQSIKASVL
EELKAVTYDS TAVRKVLGIG ETASLDDLYL EKAFEQTKAE LGQELLKVLS VDKSINTLGP
AVADAISQKI LKNKEAFLLG LTYLNRWYNV NYGTFNTKDL NAYKFDFFGN QAASTLDTII
ALGNSGMGNL RAQNNFNAYR QFLAKEKGKG DLFAYLESLR ELFLPNKTNS EWFKENTKAY
IVEARSSLPE IQAKQDNADR KSKYTIKVYD RLTQGDWGFK QMVLQLLTLP ERDVYIISNM
STIAFGSFGG YRKEGGRVLS GEELHRHVEK LVDQSAEWQR NHYDMWYNIL SPNRKDTLFR
RVIVTDGFFL YNDKGQQYWA PRNDKTSVAM YNFFGPAGKY HGDNGLGAFA NGYEVFYVYD
QMLGASGTMV YTHEMTHNSD GSIYFEGHGR REGEGPESFA TGMLESVTNV SEKGLVLNSF
YQGDKDSTTR YHTYDPVARF SSADALRDYM HGVFDVLNLL DYVEGDVVTG VLTDQQKMKW
YRKAENYNFE KTSYGKQAHA DDRIVPITAE EAAKLKSVDA LVDHNIIGRR DGWDRASFGR
NGYYVINMFA SFYAALDNPT GAPGGLMFRR RAYELLGDKG YQQGFVPYVS GQYAGQALKE
GDKTYSTWNR GDVGVVGDDL ILKNLYGSQY ESWKDLKKAM LNERYNKAQN FLRPITIEFE
AGKLDSKRQI TISSYEELQD YMYLAVLADA SAKNIDRALS DSSKSSVAQL KYRIFNAYLR
ATDDFRQSIF ER
//
