ID E6KRA5_9ACTO Unreviewed; 1031 AA.
AC E6KRA5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=Exonuclease SbcC subfamily {ECO:0000313|EMBL:EFU61463.1};
GN ORFNames=HMPREF9006_0743 {ECO:0000313|EMBL:EFU61463.1};
OS Actinomyces sp. oral taxon 180 str. F0310.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=888052 {ECO:0000313|EMBL:EFU61463.1, ECO:0000313|Proteomes:UP000006252};
RN [1] {ECO:0000313|EMBL:EFU61463.1, ECO:0000313|Proteomes:UP000006252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0310 {ECO:0000313|EMBL:EFU61463.1,
RC ECO:0000313|Proteomes:UP000006252};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU61463.1}.
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DR EMBL; AEPP01000009; EFU61463.1; -; Genomic_DNA.
DR RefSeq; WP_009212204.1; NZ_GL622194.1.
DR AlphaFoldDB; E6KRA5; -.
DR eggNOG; COG0419; Bacteria.
DR HOGENOM; CLU_004785_2_0_11; -.
DR OrthoDB; 9795626at2; -.
DR Proteomes; UP000006252; Unassembled WGS sequence.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038729; Rad50/SbcC_AAA.
DR PANTHER; PTHR32114; ABC TRANSPORTER ABCH.3; 1.
DR PANTHER; PTHR32114:SF2; ABC TRANSPORTER ABCH.3; 1.
DR Pfam; PF13476; AAA_23; 1.
DR Pfam; PF13558; SbcC_Walker_B; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000313|EMBL:EFU61463.1};
KW Hydrolase {ECO:0000313|EMBL:EFU61463.1};
KW Nuclease {ECO:0000313|EMBL:EFU61463.1}.
FT DOMAIN 6..190
FT /note="Rad50/SbcC-type AAA"
FT /evidence="ECO:0000259|Pfam:PF13476"
FT REGION 228..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 576..673
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 753..780
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1031 AA; 110299 MW; 2E99367AAAD7BF8B CRC64;
MKIRWLRITG IGPFAGTHRV DFSAFEDSGL FLLDGPTGSG KSTLIDAITF ALYGDVARTK
DASKDRLRSN HIGDEDPSEA DLVFEVGSGI YRVSRTPAYT PIGKKSQRNS RASLTRVVED
PSAPDGWRTV EAIASGPRDV GYEIPRVVGL DKDQFLQTIV LPQGKFSQFL TSTSDAREQI
LRDIFDTQIY VDFSKALTEA AAASKRGIEE RRVAAVGALE QMRSLAASLA EHDGERSGEE
AAGAASETPS LHGQADTLDA SAQDPTPVRR WADRACRDAR AAHERAQADA LDAANLAREA
AQALDRGRAL AADQAEHART TARLEELRGA EPEIDALRSR TANARRALAV APYASSAASA
ARRLEEAADR VASCARGLAA EEDIPLSSQD LTLEVVADLL ARAHALRDEA TRTLGALEAT
LVQERSLPGL AEEISALEES HRGALAAVAT LESQRDTLPA VIERAQASLT LMRSDADALP
DKRAALHALD RRLEASRQAD LLRAALPGAS EELREATAGA KLANAAAADA HDLWIAQSAS
AIARELEDEV PCPVCGSPDH PCPAPPLDGE ITREQVADLD RARDRAEDAL RDARSTHQDM
VRRIAQLNEA AAGPTALLET QRDQAALEVA ALDALKPRIA SLEEDLAQVR EQLDGITDEL
TRARERAASL ASQLAERRSA LAHTQRHVEG ERQGFPSLEA RAAHLDQRAQ RAASTIGACS
DWDGARRAHD EALRSLARAL ESQELASDTW ERLLLTRDEV DALETRINEH EKELYATRDA
LTSDRLVRAA ACPEPDIAAL ADASQRAGDA SAEATRRAGR LEQHCAQLDA ARESLGASLA
ALADAREQAG PIRRLADIAS ASGPENLVST PLSAWVLIAR LEEVLASANP RLAAISSGRY
ELVAVPDDGT TSRKSGLGLA VIDHDTDSVR SPRTLSGGET FYTSLALALG LADVVSAEAG
GVELRTMFID EGFGSLDSHT LSLVMAQLQA LRCAGRTVGV ISHVEEMATQ IADQIQVRPL
GEHGSTLRVR A
//
