ID E6LYJ0_9ACTO Unreviewed; 677 AA.
AC E6LYJ0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=DNA (Cytosine-5-)-methyltransferase {ECO:0000313|EMBL:EFU80233.1};
GN ORFNames=HMPREF0388_0927 {ECO:0000313|EMBL:EFU80233.1};
OS Mobiluncus curtisii ATCC 51333.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Mobiluncus.
OX NCBI_TaxID=887326 {ECO:0000313|EMBL:EFU80233.1, ECO:0000313|Proteomes:UP000005573};
RN [1] {ECO:0000313|EMBL:EFU80233.1, ECO:0000313|Proteomes:UP000005573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51333 {ECO:0000313|EMBL:EFU80233.1,
RC ECO:0000313|Proteomes:UP000005573};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU80233.1}.
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DR EMBL; AEPY01000007; EFU80233.1; -; Genomic_DNA.
DR RefSeq; WP_004009344.1; NZ_GL622340.1.
DR AlphaFoldDB; E6LYJ0; -.
DR HOGENOM; CLU_029607_1_0_11; -.
DR Proteomes; UP000005573; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR022221; TypeIII_RM_meth.
DR PANTHER; PTHR13370:SF32; DNA ADENINE METHYLTRANSFERASE YHDJ; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR Pfam; PF12564; TypeIII_RM_meth; 1.
DR PIRSF; PIRSF015855; TypeIII_Mtase_mKpnI; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EFU80233.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFU80233.1}.
FT DOMAIN 37..92
FT /note="Type III restriction/modification enzyme methylation
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF12564"
FT DOMAIN 195..539
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 677 AA; 76706 MW; F331FC4F568FEFE3 CRC64;
MTFLQELETV LKGDERFVSQ DGQLLKPRVQ DAVTQLDAQL IRQLMASPAL KEHFFKYIDG
VTIFDQEKFM WVVNSKEFLP DSYTSYRNKI GLSANDHDLL TQSNEVALVW PYRDCVLEGG
QDKEDDKRDE IFYNETLAPD EVGRLLAPKA FRNATRYSAE GEEHVTEFDE NDNLIIKGNN
LLALSSLLER YEGQVKCIYI DPPYNTGTDS FGYNDRFNHS TWLTFMKNRL GLARQLLRAD
GFIFVQSDDN EQAYLKVLMD EIFGTENFIN VISVKTKVGG VSGSSQGKSL RDELEYINMY
YKSRMDENAV INPTYVFTKL DEHIRAYQES GRSWKYTSVL TQLGEKKLLH EDADSGERLF
GYSQVETASV GAFAKKQGIS ESEVYRDHAD KIFQTTNAQS SVRGRVMKLA KQFGDFEMVG
FEYTPMKGKN EGAVTEVLYK GAQQRMMMFL SDAVVQRDGS FQYRDRVGTL WTDLQYNNLT
REGNVAFPNG KKPESLIERI LLLTTQPGDI VCDFFLGSGT TAAVAHKMGR RYIGVEQMDY
VSTVTIPRLQ KVIAGEQGGV SKAQEWKGGG SFVYVELAEQ SEKLMHELQD AKTTDEVQGV
LDRATERGLL RPSVLPDQLT SSVSEFEQLS LDDQKRAVAE LIDKNRLYVN ASDVEDAELG
LSEVDIAFTK SFYKKGE
//
