ID E6PFH5_9ZZZZ Unreviewed; 658 AA.
AC E6PFH5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 13-SEP-2023, entry version 36.
DE SubName: Full=UvrABC system protein C (Protein uvrC) (Excinuclease ABC subunit C) {ECO:0000313|EMBL:CBH75211.1};
GN Name=uvrC {ECO:0000313|EMBL:CBH75211.1};
GN ORFNames=CARN1_1536 {ECO:0000313|EMBL:CBH75211.1};
OS mine drainage metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=410659 {ECO:0000313|EMBL:CBH75211.1};
RN [1] {ECO:0000313|EMBL:CBH75211.1}
RP NUCLEOTIDE SEQUENCE.
RA Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA Le Paslier D.;
RT "Diversity of trophic interactions inside an arsenic-rich microbial
RT ecosystem.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBH75211.1}.
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DR EMBL; CABL01000006; CBH75211.1; -; Genomic_DNA.
DR AlphaFoldDB; E6PFH5; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0009381; F:excinuclease ABC activity; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd10434; GIY-YIG_UvrC_Cho; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR Gene3D; 3.30.420.340; UvrC, RNAse H endonuclease domain; 1.
DR HAMAP; MF_00203; UvrC; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR047296; GIY-YIG_UvrC_Cho.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004791; UvrC.
DR InterPro; IPR001162; UvrC_RNase_H_dom.
DR InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR NCBIfam; TIGR00194; uvrC; 1.
DR PANTHER; PTHR30562:SF1; UVRABC SYSTEM PROTEIN C; 1.
DR PANTHER; PTHR30562; UVRC/OXIDOREDUCTASE; 1.
DR Pfam; PF01541; GIY-YIG; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF08459; UvrC_RNaseH_dom; 1.
DR SMART; SM00465; GIYc; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
DR PROSITE; PS50151; UVR; 1.
DR PROSITE; PS50165; UVRC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881}.
FT DOMAIN 15..94
FT /note="GIY-YIG"
FT /evidence="ECO:0000259|PROSITE:PS50164"
FT DOMAIN 203..238
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT DOMAIN 254..533
FT /note="UvrC family homology region profile"
FT /evidence="ECO:0000259|PROSITE:PS50165"
FT COILED 199..226
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 658 AA; 73946 MW; 011AF05DE0E48E70 CRC64;
MATAPLELTL AQLPDAPGVY QMLAADGEVL YIGKAISLRN RVRSYFQGSA QHHPRITAMV
ARVVDIETTV VGNEIEALIL EANLIKRYQP PFNVRMRDDK RYPYLKVTNE PFARVHFTRT
LAPDGARYFG PFTNARDLRE LIDLVRMVFP LRTCREPIDG KRARPCLQYH IKRCMAPCVG
YQSREEYDAI VDDVVLFLEG KHEALLARLN AEMETAANEM RFEAAASIRD RIIAVRRVTE
RQRVVWRSRI DMDLIACARS QGQACMEVFV VRGGKLVGQE HVILDGVSAR EPEEIFAEFL
TQFYSARAAG EERRTFSTIA EGRIARDNAA PAPASARARP YAASVVPKEL LLEAMPEDRE
EIERWLSGVK GQRVRILVPQ RGERADYLRL VARNAEQHLK AFLAHQEVQE SAQARALDEL
AQALELPDLP RRIECYDISN VQGTNPVASM VVFVEGRAKK SAYRKFAIQY KHGPNDFEMM
REVLRRRLRY LAQREEDDAL GVDRTKRERF SARPDLLLVD GGKGQLGVAV EVLDELGLAG
IPVAGLAKEH EWLYLPERSE PIVLPPGSPA LHLVIRVRDE AHRFAITFHR SKRDKAMIRS
ALDEVPGLGP VRRKRLLAAF GSVAAIKRAE LDAVAAVKGM TPALAAAIRS HLGERSPG
//
