ID E6R5K8_CRYGW Unreviewed; 606 AA.
AC E6R5K8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 03-MAY-2023, entry version 55.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ADV21542.1};
GN OrderedLocusNames=CGB_D1650W {ECO:0000313|EMBL:ADV21542.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV21542.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV21542.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
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DR EMBL; CP000289; ADV21542.1; -; Genomic_DNA.
DR RefSeq; XP_003193329.1; XM_003193281.1.
DR AlphaFoldDB; E6R5K8; -.
DR GeneID; 10191054; -.
DR KEGG; cgi:CGB_D1650W; -.
DR VEuPathDB; FungiDB:CGB_D1650W; -.
DR eggNOG; KOG2522; Eukaryota.
DR HOGENOM; CLU_012487_1_1_1; -.
DR OrthoDB; 102595at2759; -.
DR Proteomes; UP000007805; Chromosome D.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:InterPro.
DR GO; GO:0001731; P:formation of translation preinitiation complex; IEA:InterPro.
DR CDD; cd11608; eIF2D_C; 1.
DR Gene3D; 3.10.400.20; -; 1.
DR Gene3D; 3.30.780.10; SUI1-like domain; 1.
DR InterPro; IPR039757; EIF2D.
DR InterPro; IPR039759; eIF2D_SUI1.
DR InterPro; IPR041366; Pre-PUA.
DR InterPro; IPR001950; SUI1.
DR InterPro; IPR036877; SUI1_dom_sf.
DR InterPro; IPR036885; SWIB_MDM2_dom_sf.
DR InterPro; IPR003121; SWIB_MDM2_domain.
DR PANTHER; PTHR12217; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR PANTHER; PTHR12217:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 2D; 1.
DR Pfam; PF17832; Pre-PUA; 1.
DR Pfam; PF01253; SUI1; 1.
DR SUPFAM; SSF55159; eIF1-like; 1.
DR SUPFAM; SSF47592; SWIB/MDM2 domain; 1.
DR PROSITE; PS50296; SUI1; 1.
DR PROSITE; PS51925; SWIB_MDM2; 1.
PE 4: Predicted;
FT DOMAIN 412..498
FT /note="DM2"
FT /evidence="ECO:0000259|PROSITE:PS51925"
FT DOMAIN 514..590
FT /note="SUI1"
FT /evidence="ECO:0000259|PROSITE:PS50296"
FT REGION 220..249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 222..241
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 66109 MW; 90C5855A6467B7C2 CRC64;
MFKKPLAHQS NATPIRSSAR RQLLSAILEQ YPSLLAQDET DDHSKKELSK LILPEGVRIA
TFETSTGLEG TFWLSPNGDP LWMTLGRNSK EYIPTLFLLS LPLPRPPLPI IQIYHPLPPP
ILTGAPLFIP AVRNIDKPHR LPAVSKSQLV AFVTSPTKDD SVHYIGVGRV EAEGGMKGAW
ERRVNNLMDG GDREEGKFSD ILCIVDDHLW DLGSKPTLST FTLPPPQNPL AAPPEGFEPM
PKSSSPPAIQ QLSISAEDGS KASIPVSTSL SASEISSLLS LSLLQALSGL QPSAFPMSAS
LLYSSHILPS RPAYIPKAER DEVVIGKSDW KKLAKWMKEA SKEGIVKIKE NKGEVTVVSF
DSRHPSLQAH VDYMTIAQEE AKASKKAARE AASDQSTNGG KSSNKQSLDI EELWKPAGGA
ISFWEACGIS KSDYHPPPTL KQALDGYITS HNLLDPTNHK FILLDDELGR AVGIKKPEAG
DKMARDEILN KLKNGVSWVV SIGGTIKKGA LQPITMTVKS RGGRRTVTHV TGLELFNVDI
ESFAEDMRKR CAGSASIQPR EGVSPKLGLQ EVLVQGSQQK LITEALLERG VPKRWIKDEG
DKKGKK
//
