ID E6SCP0_INTC7 Unreviewed; 501 AA.
AC E6SCP0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Fumarate reductase/succinate dehydrogenase flavoprotein domain protein {ECO:0000313|EMBL:ADU49644.1};
GN OrderedLocusNames=Intca_3160 {ECO:0000313|EMBL:ADU49644.1};
OS Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC
OS 12989 / 7 KIP).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Intrasporangium.
OX NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU49644.1, ECO:0000313|Proteomes:UP000008914};
RN [1] {ECO:0000313|EMBL:ADU49644.1, ECO:0000313|Proteomes:UP000008914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC {ECO:0000313|Proteomes:UP000008914};
RX PubMed=21304734; DOI=10.4056/sigs.1263355;
RA Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S., Cheng J.F.,
RA Detter C., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Pati A., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Pukall R., Sikorski J.,
RA Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Lapidus A.;
RT "Complete genome sequence of Intrasporangium calvum type strain (7 KIP).";
RL Stand. Genomic Sci. 3:294-303(2010).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CP002343; ADU49644.1; -; Genomic_DNA.
DR RefSeq; WP_013493956.1; NC_014830.1.
DR AlphaFoldDB; E6SCP0; -.
DR STRING; 710696.Intca_3160; -.
DR KEGG; ica:Intca_3160; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_011398_4_6_11; -.
DR OrthoDB; 9813348at2; -.
DR Proteomes; UP000008914; Chromosome.
DR GO; GO:0033765; F:steroid dehydrogenase activity, acting on the CH-CH group of donors; IEA:UniProt.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008914}.
FT DOMAIN 12..462
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 501 AA; 52979 MW; 3094BAA31BC35317 CRC64;
MSTDEQHEHP YDVIVVGGGI AGLSAALSAT ENGARVALLE RSVEAETGGN TRYTEAYLRM
KSLDEVSDGL ADTLVDDFMG HPDPGITADS GLDWERRNPL LRAHQVIDLD YVARFEDNAG
PTLRWLESHG ISFGQLPTLF LTVSTTRMAP VGGGLALVET LGAKARALGV DVHFQTTARS
LRVDDAGRVT GVEAVDASGA RRVFAGNVVL ASGGYQGNAE LMARYHGPLG MLARPVARGG
NYNKGEGIEM AMAIGAATAG NFALFHAEPV DPRSPDPEAA IMAFTYGILV NVDGQRFVDE
ARGPIDAWYE RTTRDIHAQP RGMAWMILDA RAQAIPNLKT AIRSEEKPVR ADTIADLATQ
IEVDPATLEA TVAAYNAACP PGEWDPTRPD GLATQGVTPP KSNWAKPIES GPFIAYPIMC
ANVFTFGGLK VDATSRVVDR DGRIIAGLYA AGEMTGLYYS NYTGSTSVLR GATFGKIAGA
DAAARAASER SASTAPAEVG S
//
