ID E6SN84_BACT6 Unreviewed; 696 AA.
AC E6SN84;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN OrderedLocusNames=Bache_2794 {ECO:0000313|EMBL:ADV44737.1};
OS Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG
OS 15421 / P 36-108).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=693979 {ECO:0000313|EMBL:ADV44737.1, ECO:0000313|Proteomes:UP000008630};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P 36-108;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Bacteroides helcogenes P 36-108.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV44737.1, ECO:0000313|Proteomes:UP000008630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108
RC {ECO:0000313|Proteomes:UP000008630};
RX PubMed=21475586; DOI=10.4056/sigs.1513795;
RA Pati A., Gronow S., Zeytun A., Lapidus A., Nolan M., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brambilla E.,
RA Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Lucas S.;
RT "Complete genome sequence of Bacteroides helcogenes type strain (P 36-
RT 108).";
RL Stand. Genomic Sci. 4:45-53(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
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DR EMBL; CP002352; ADV44737.1; -; Genomic_DNA.
DR AlphaFoldDB; E6SN84; -.
DR STRING; 693979.Bache_2794; -.
DR KEGG; bhl:Bache_2794; -.
DR PATRIC; fig|693979.3.peg.2927; -.
DR eggNOG; COG3525; Bacteria.
DR HOGENOM; CLU_007082_5_0_10; -.
DR OrthoDB; 1090159at2; -.
DR Proteomes; UP000008630; Chromosome.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:ADV44737.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADV44737.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008630}.
FT DOMAIN 28..155
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 159..503
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 334
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 696 AA; 78743 MW; AB4F7EC211AE90BD CRC64;
MPKHHFIIHV LLITAFFGMS RNEVNAQSVI PVPLKMEQGN GIFRISKETK IYANLKGKEK
KNFNDYLTTL PAPFNVGIST KNGKNENTII LHKAKQGTER AISGPEDYVL EITDRKATIC
AYSDAGLFYG LQTLLQLAEE DGNGTWAVKN IRVEDSPRFS YRGFMLDVSR HFRSKEFVKK
QIDALAYFKL NRLHLHLTDG AGWRIEIKKY PRLTEFAAWR PEANWKKWWF GENARKYCEQ
SDPRAQGGFY TQDDIRELVN YAAERHITII PEIEMPAHSE EVLAAYPELS CPEEPYKSAD
FCVGNEKTFT FLENVLTEVM KLFPSEYIHI GGDEAGKAAW KTCPKCKQRM QNEDLKDVNE
LQSYLIHRIE TFLNAHGRKL LGWDEIMEGG LAPNATVMSW RGEEGGINAV KAGHRAIMSP
GSHCYIDGYQ DAPYSQPEAI GGYLPLSKVY DYNPIPAALT TEESKLIYGV QANLWCEYIP
TAEHCEYMIY PRILALAEVA WSAPARKSYT DFHPRALKAV EWLKAQGYHP FDLKNEIGNR
PEASQPVKHL ALGKSVKYNA PYNASYAAHG DKSLTDGVCG GWTYSDGIWQ GFISSNRLDV
VIDMETETEL HSISADFLQV VGPEVFLPGQ IIISVSSNGT EFTELSRTTY PVVKSDIVAI
KRYGWQGEAR ARYIRYQALA GQEFGGWIFT DEIVVK
//
