ID E6UGI9_RUMA7 Unreviewed; 408 AA.
AC E6UGI9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE RecName: Full=Beta-glucanase {ECO:0000256|ARBA:ARBA00014569};
DE EC=3.2.1.73 {ECO:0000256|ARBA:ARBA00012690};
DE AltName: Full=1,3-1,4-beta-D-glucan 4-glucanohydrolase {ECO:0000256|ARBA:ARBA00031665};
DE AltName: Full=Endo-beta-1,3-1,4 glucanase {ECO:0000256|ARBA:ARBA00029771};
DE AltName: Full=Lichenase {ECO:0000256|ARBA:ARBA00029722};
DE Flags: Precursor;
GN OrderedLocusNames=Rumal_2637 {ECO:0000313|EMBL:ADU23112.1};
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329 {ECO:0000313|EMBL:ADU23112.1, ECO:0000313|Proteomes:UP000006919};
RN [1] {ECO:0000313|EMBL:ADU23112.1, ECO:0000313|Proteomes:UP000006919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7
RC {ECO:0000313|Proteomes:UP000006919};
RX PubMed=21914885; DOI=10.1128/JB.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-
CC glucans containing (1->3)- and (1->4)-bonds.; EC=3.2.1.73;
CC Evidence={ECO:0000256|ARBA:ARBA00000481};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family.
CC {ECO:0000256|ARBA:ARBA00006865}.
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DR EMBL; CP002403; ADU23112.1; -; Genomic_DNA.
DR AlphaFoldDB; E6UGI9; -.
DR STRING; 697329.Rumal_2637; -.
DR KEGG; ral:Rumal_2637; -.
DR eggNOG; COG2273; Bacteria.
DR HOGENOM; CLU_674190_0_0_9; -.
DR Proteomes; UP000006919; Chromosome.
DR GO; GO:0042972; F:licheninase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd02175; GH16_lichenase; 1.
DR CDD; cd00161; RICIN; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.80.10.50; -; 3.
DR InterPro; IPR044791; Beta-glucanase/XTH.
DR InterPro; IPR008264; Beta_glucanase.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000757; GH16.
DR InterPro; IPR008263; GH16_AS.
DR InterPro; IPR035992; Ricin_B-like_lectins.
DR InterPro; IPR000772; Ricin_B_lectin.
DR PANTHER; PTHR31062; XYLOGLUCAN ENDOTRANSGLUCOSYLASE/HYDROLASE PROTEIN 8-RELATED; 1.
DR PANTHER; PTHR31062:SF185; XYLOGLUCAN ENDOTRANSGLUCOSYLASE_HYDROLASE PROTEIN 6-RELATED; 1.
DR Pfam; PF00722; Glyco_hydro_16; 1.
DR Pfam; PF14200; RicinB_lectin_2; 1.
DR PRINTS; PR00737; GLHYDRLASE16.
DR SMART; SM00458; RICIN; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50370; Ricin B-like lectins; 1.
DR PROSITE; PS01034; GH16_1; 1.
DR PROSITE; PS51762; GH16_2; 1.
DR PROSITE; PS50231; RICIN_B_LECTIN; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:ADU23112.1}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..408
FT /note="Beta-glucanase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003213020"
FT DOMAIN 39..244
FT /note="GH16"
FT /evidence="ECO:0000259|PROSITE:PS51762"
FT REGION 242..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 45967 MW; 0A574E2EC4A121CD CRC64;
MKVKRIVSFL TAAAISASMM LSASAAERFN GSYFGTGFDS YEWGTMEASD GWSNGGMFDC
TWSRNNVQFS GGKMNLSITG NSWQGYKGAE YRTTKTFGFG MYDVSMKPIK NDGVVSSFFT
YTGPSDGTVW DEIDIEFLGK NTNQVQFNYY TRGQGNHEYV YNLGFDASQS FHQYGFYWDK
SSITWYVDKK PVYTAYRDIP QTPGKIMMNV WNGKGVDEWL NHYNGRAPLT AQYDWISYTA
PNGSSNTQQK QNNNNQQNNN NNSGSFNSRQ KYAIKSVNSG KALDVSWGSK DDGANVLQYR
YSGYENQKWY LEKQWDGYYV IKCANSGKAL DVSWGDKNDG ANVQQCSVNG SDAQKWELRK
VGSSYALINK NSGKALDVEG RSKNDNANVL QWRYTGASNQ LWNIEAVN
//
