ID   E6ZMD6_SPORE            Unreviewed;       582 AA.
AC   E6ZMD6;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Cyclase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=sr14676 {ECO:0000313|EMBL:CBQ68393.1};
OS   Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX   NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ68393.1, ECO:0000313|Proteomes:UP000008867};
RN   [1] {ECO:0000313|EMBL:CBQ68393.1, ECO:0000313|Proteomes:UP000008867}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX   PubMed=21148393; DOI=10.1126/science.1195330;
RA   Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA   Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA   Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA   Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA   Kahmann R.;
RT   "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL   Science 330:1546-1548(2010).
CC   -!- SIMILARITY: Belongs to the Cyclase 1 superfamily.
CC       {ECO:0000256|ARBA:ARBA00007865}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FQ311431; CBQ68393.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6ZMD6; -.
DR   EnsemblFungi; CBQ68393; CBQ68393; sr14676.
DR   VEuPathDB; FungiDB:sr14676; -.
DR   eggNOG; ENOG502QW43; Eukaryota.
DR   HOGENOM; CLU_030671_6_0_1; -.
DR   OrthoDB; 2076300at2759; -.
DR   Proteomes; UP000008867; Chromosome 10.
DR   GO; GO:0004061; F:arylformamidase activity; IEA:InterPro.
DR   GO; GO:0019441; P:tryptophan catabolic process to kynurenine; IEA:InterPro.
DR   Gene3D; 3.50.30.50; Putative cyclase; 1.
DR   InterPro; IPR007325; KFase/CYL.
DR   InterPro; IPR037175; KFase_sf.
DR   PANTHER; PTHR34861; -; 1.
DR   PANTHER; PTHR34861:SF10; CYCLASE; 1.
DR   Pfam; PF04199; Cyclase; 1.
DR   SUPFAM; SSF102198; Putative cyclase; 1.
PE   3: Inferred from homology;
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   582 AA;  63076 MW;  C89906EA1D296B86 CRC64;
     MVDSNTKAAT PTSGSNDGDD TRQQHDDNDE SNRQRIASIA SRFGGLAAQA STQAAHKGTQ
     TAADAGQQVA EAVKSTRTAA AHQTAGLLQA MALTTKNAFS SADKEKHANN TSSSSKAWYE
     YESPLHARRR LAEYESPLHA RRRLAAIASQ LGLATSSAQQ APSLLAALSS SSTSSRSPSA
     SSSKASAEKW ATVALPDYKH LPSHGGWPGC AWDVWGPGDQ LGTINLLTES LVLKATKEQV
     KIGRTVSLNW PVHLPAEPFF RRKALTHKPF GKGGPGYTGP RDAYIAGVRA KQPDVVVRSD
     DKVPVCDEIL ELNTQSGSQW DGLRHFGHQP LNVFYGGASR ASIQDTFDDT SPQPADPQAW
     DSEQAKKRNA LGIHHLAQHG ICGRGVLLDV FDYLSHHGTH HVKRDDYEWS HWQAYGGGKG
     YDPRTGFRIT VDDLLATAKH QNVTLRRGDI LLVRSGFTAR YYSLTPAERA EWSNPAPASG
     RAGMEFAGVE QSDAMKAFLW DHHFAAVAGD SPAFEARPTK QGECMLHETL LAMWGMPIGE
     LFDLEALAQT CKEQGRWSFY FSSWPLNLFG GVASCANASA TF
//