ID E7BKT5_CRASI Unreviewed; 133 AA.
AC E7BKT5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Bindin F-lectin {ECO:0000313|EMBL:ADK70396.1};
DE Flags: Fragment;
OS Crassostrea sikamea (Kumamoto oyster).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=94324 {ECO:0000313|EMBL:ADK70396.1};
RN [1] {ECO:0000313|EMBL:ADK70396.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S6 {ECO:0000313|EMBL:ADK70396.1};
RX PubMed=20549283; DOI=10.1007/s10126-010-9304-0;
RA Wu Q., Li L., Zhang G.;
RT "Crassostrea angulata bindin gene and the divergence of fucose-binding
RT lectin repeats among three species of Crassostrea.";
RL Mar. Biotechnol. 13:327-335(2011).
CC -!- FUNCTION: Acts as a defensive agent. Recognizes blood group fucosylated
CC oligosaccharides including A, B, H and Lewis B-type antigens. Does not
CC recognize Lewis A antigen and has low affinity for monovalent haptens.
CC {ECO:0000256|ARBA:ARBA00002219}.
CC -!- SUBUNIT: Homotrimer. {ECO:0000256|ARBA:ARBA00011233}.
CC -!- SIMILARITY: Belongs to the fucolectin family.
CC {ECO:0000256|ARBA:ARBA00010147}.
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DR EMBL; GQ408889; ADK70396.1; -; mRNA.
DR AlphaFoldDB; E7BKT5; -.
DR GO; GO:0042806; F:fucose binding; IEA:UniProt.
DR GO; GO:0010185; P:regulation of cellular defense response; IEA:UniProt.
DR GO; GO:0001868; P:regulation of complement activation, lectin pathway; IEA:UniProt.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR006585; FTP1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR PANTHER; PTHR45713:SF6; F5_8 TYPE C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45713; FTP DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR SMART; SM00607; FTP; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 2: Evidence at transcript level;
KW Lectin {ECO:0000256|ARBA:ARBA00022734}.
FT DOMAIN 4..133
FT /note="Fucolectin tachylectin-4 pentraxin-1"
FT /evidence="ECO:0000259|SMART:SM00607"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADK70396.1"
FT NON_TER 133
FT /evidence="ECO:0000313|EMBL:ADK70396.1"
SQ SEQUENCE 133 AA; 14877 MW; 60CE896EC0ECBE2B CRC64;
VGGSKNLALG KKTYMSSVYG KYGGQYCVNG NTKDYCHTRG QNNPWIRIDL GAVYKVDRVV
IHNRNTWGGR FRNAFIHVGE SISRLRKCGY FKGPGRNSQK ITIKCPGGMK GRFIQIQARA
KTFLNLADVQ VFG
//
