ID E7BR09_MYLPI Unreviewed; 222 AA.
AC E7BR09;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 22-FEB-2023, entry version 38.
DE SubName: Full=Homeodomain protein HoxA9a {ECO:0000313|EMBL:ADV40679.1};
DE Flags: Fragment;
GN Name=hoxa9a {ECO:0000313|EMBL:ADV40679.1};
OS Mylopharyngodon piceus (Black carp) (Leuciscus piceus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Xenocyprididae; Xenocypridinae; Mylopharyngodon.
OX NCBI_TaxID=75356 {ECO:0000313|EMBL:ADV40679.1};
RN [1] {ECO:0000313|EMBL:ADV40679.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20976012; DOI=10.1371/journal.pone.0013508;
RA Tao W., Zou M., Wang X., Gan X., Mayden R.L., He S.;
RT "Phylogenomic analysis resolves the formerly intractable adaptive
RT diversification of the endemic clade of east Asian Cyprinidae
RT (Cypriniformes).";
RL PLoS ONE 5:E13508-E13508(2010).
CC -!- FUNCTION: Sequence-specific transcription factor which is part of a
CC developmental regulatory system that provides cells with specific
CC positional identities on the anterior-posterior axis.
CC {ECO:0000256|ARBA:ARBA00003263}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the Abd-B homeobox family.
CC {ECO:0000256|ARBA:ARBA00006317}.
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DR EMBL; GU217855; ADV40679.1; -; Genomic_DNA.
DR AlphaFoldDB; E7BR09; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR006711; Hox9_activation_N.
DR InterPro; IPR017112; HXA9/HXB9/HXC9.
DR PANTHER; PTHR45970; AGAP004664-PA; 1.
DR PANTHER; PTHR45970:SF3; HOMEOBOX PROTEIN HOX-A9; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR Pfam; PF04617; Hox9_act; 1.
DR PIRSF; PIRSF037109; Homeobox_Hox9; 1.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108,
KW ECO:0000256|RuleBase:RU000682}.
FT DOMAIN 178..222
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT REGION 109..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..165
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADV40679.1"
FT NON_TER 222
FT /evidence="ECO:0000313|EMBL:ADV40679.1"
SQ SEQUENCE 222 AA; 24562 MW; D05735C6CAC6C664 CRC64;
GTLTGYYIDS LVMPDNEENR FSSGSGLIQH RPSVLPTDHT ELGPCTFPAK QPVYGGSGWG
HIPTHFSSGV PSVYQPHTQP PVTGDYVQSW LLDSACGLPF TELPTVHHYH TKPDTNRTND
DGTEASSNAV IPPGDFINGA CSTDTEKVSG RTAEKGGDIE EKPGAHPDNP VSNWLHASST
RKKRCPYTKH QILELEKEFL FNSYLTRDRR YEVARLLNLT ER
//
