ID E7CGG9_BACTU Unreviewed; 426 AA.
AC E7CGG9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Xanthine/uracil/vitamin C permease {ECO:0000313|EMBL:ADU03108.1};
GN ORFNames=pBMB0558_00210 {ECO:0000313|EMBL:ADU03108.1};
OS Bacillus thuringiensis serovar chinensis CT-43.
OG Plasmid pBMB0558 {ECO:0000313|EMBL:ADU03108.1}.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC Bacillus cereus group.
OX NCBI_TaxID=541229 {ECO:0000313|EMBL:ADU03108.1};
RN [1] {ECO:0000313|EMBL:ADU03108.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CT-43 {ECO:0000313|EMBL:ADU03108.1};
RC PLASMID=pBMB0558 {ECO:0000313|EMBL:ADU03108.1};
RX PubMed=20864531; DOI=10.1074/jbc.M110.148387;
RA Liu X.Y., Ruan L.F., Hu Z.F., Peng D.H., Cao S.Y., Yu Z.N., Liu Y.,
RA Zheng J.S., Sun M.;
RT "Genome-wide Screening Reveals the Genetic Determinants of an Antibiotic
RT Insecticide in Bacillus thuringiensis.";
RL J. Biol. Chem. 285:39191-39200(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; HM037272; ADU03108.1; -; Genomic_DNA.
DR AlphaFoldDB; E7CGG9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF1; PURINE PERMEASE YWDJ-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:ADU03108.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 131..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..338
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 344..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 376..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 404..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 426 AA; 46134 MW; B8E22827EBFBF59D CRC64;
MNKKYFNTSF SILQWFVFLL ANAIALPIII GGIFHLSVED ISTLMQRTFL VVGISSFIQA
WFGHRYPIAD GPAGSWVSIF VILGQVAMHQ GQSAKDVLQL LEGGLIIAGI LLFVLGITGL
VHQILRLFTP LVTGTFLLIL ALQLSGVLLK GMMGLQGSAT HPDYPTAIIA LFVFAFITFL
SIKGTGWMKR YAVLLGISCG WLLYTLLGES SYMPTHTTLV KLPEIFAWGT PRLDIGMTLT
ATLFTFLLVA NTIAAISAVK QVAPLSKENE KQTLNRGVWV GGISHIISSL FSTIGIVPLP
ATAGFIQLTG QRKLKSFLIA SLILAGISFV PSIVSFISLL PGPIANAALL ATFVQVIGIS
FQSILSEELN QRRLTILGIT LLISLGIMFL PESAFSGIPS SLQYVLRNGL LVGTVIVILL
EQFWKE
//
