ID E7EDR9_PIG Unreviewed; 545 AA.
AC E7EDR9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Type I interferon receptor {ECO:0000313|EMBL:ADR80133.1};
GN Name=IFNAR2 {ECO:0000313|EMBL:ADR80133.1};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|EMBL:ADR80133.1};
RN [1] {ECO:0000313|EMBL:ADR80133.1}
RP NUCLEOTIDE SEQUENCE.
RA Zhao X., Cheng G., Zheng Z.X.;
RT "Porcine type I interferon receptors.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; HQ665551; ADR80133.1; -; mRNA.
DR AlphaFoldDB; E7EDR9; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR015373; Interferon/interleukin_rcp_dom.
DR PANTHER; PTHR20859:SF84; INTERFERON ALPHA_BETA RECEPTOR 2; 1.
DR PANTHER; PTHR20859; INTERFERON/INTERLEUKIN RECEPTOR; 1.
DR Pfam; PF09294; Interfer-bind; 1.
DR Pfam; PF01108; Tissue_fac; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ADR80133.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..118
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF01108"
FT DOMAIN 134..236
FT /note="Interferon/interleukin receptor"
FT /evidence="ECO:0000259|Pfam:PF09294"
FT REGION 357..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 439..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..377
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 441..474
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 475..513
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 545 AA; 61086 MW; 9D4D1C4C7F666F09 CRC64;
MLLSQNVSVI GPVNLYPMVH ISLVFGISFI LSDSSDESCT LKMRFRNSQS ILSWELKNHL
VVPTHYTLWY TIMSKQENMK MVETCANITR SFCDLTDVWI NLTETYIPRV VAFRENTALV
TCMGSFFMAT DTMSLDPPDF EVAGFTDHIN VNVNFQSVVS KTLNEEELQF YLVQVIEKPS
GGIAKKHKPR IKGNITENFN YVIDKLIPNT NYCVSVYFEP KDQNKINRSP LKCTFIQRES
ESSESTKLGG IITLFVIAAV FISTIVTLKR IGYICLRNDF PKVLTFSKLS AWVFPELPPL
ENVSTVEIIH NHRKKKEWNY NYDDESDSDS EAAPQKNAGG YTMHRLRPLC PASTSSATLE
DYCSDPDTED PDLPEPEAAA EAPEAPGPSA WQSEYQSGGY ERRVSLQQDP YFPEDSSPPE
GSQDRIVFNV DLKSVCVRVL DDDDDDSDDD DDNDNDDDDE DDNGDEDEDD DSEVTPMLSS
QPEGTAGLED ATETESNLLE VSGKGTQQPF FPSPSMARPG PKDASSDKSD TSESDADIRD
GYIMR
//
