ID E7NCM0_9ACTO Unreviewed; 371 AA.
AC E7NCM0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EFW26101.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:EFW26101.1};
GN ORFNames=HMPREF9057_02552 {ECO:0000313|EMBL:EFW26101.1};
OS Actinomyces sp. oral taxon 171 str. F0337.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=706439 {ECO:0000313|EMBL:EFW26101.1, ECO:0000313|Proteomes:UP000005722};
RN [1] {ECO:0000313|EMBL:EFW26101.1, ECO:0000313|Proteomes:UP000005722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:EFW26101.1,
RC ECO:0000313|Proteomes:UP000005722};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW26101.1}.
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DR EMBL; AECW01000451; EFW26101.1; -; Genomic_DNA.
DR AlphaFoldDB; E7NCM0; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_055968_0_0_11; -.
DR Proteomes; UP000005722; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFW26101.1}.
FT DOMAIN 1..277
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 371 AA; 37845 MW; 487DF32D2E9ABD91 CRC64;
MLIVGTGLLG TSLALALRAA GVEVQLSDTS PTSLALARDM GAGTLHGKDS PEPRVIVVAT
PPDVTADVVV AQLSAHPSAV VTDVASVKER VVNEVRDRAR AEARRYVGSH PMAGRECSGA
GAADSDLFAG RPWVVVGQDS DPQAELVVRN LAVDVGASPV RMGAAEHDAA VAAVSHMPQL
VSSLVAARLE GLGEGTLALS GQGLRDVTRI AASDPRLWSA IIVGNAGPVV DLLRRISDDL
GALITGIEAA TYDPDGPEYA GPGAARVVAP GAVGAVTDIM TRGNAGRARI PGKHGGAPRR
YTEVQVLVPD AAGELGRLFS DVGAAGVNIE DFSLEHSAGQ SAGIALISVL PAVARRLEEA
LDAQGWRVVA V
//
