ID E7NT34_TREPH Unreviewed; 751 AA.
AC E7NT34;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE SubName: Full=Transporter, major facilitator family protein {ECO:0000313|EMBL:EFW38252.1};
GN ORFNames=HMPREF9554_01225 {ECO:0000313|EMBL:EFW38252.1};
OS Treponema phagedenis F0421.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW38252.1, ECO:0000313|Proteomes:UP000004157};
RN [1] {ECO:0000313|EMBL:EFW38252.1, ECO:0000313|Proteomes:UP000004157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0421 {ECO:0000313|EMBL:EFW38252.1,
RC ECO:0000313|Proteomes:UP000004157};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW38252.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEFH01000097; EFW38252.1; -; Genomic_DNA.
DR RefSeq; WP_002697529.1; NZ_GL638032.1.
DR AlphaFoldDB; E7NT34; -.
DR STRING; 162.TPHV1_70039; -.
DR eggNOG; COG1413; Bacteria.
DR eggNOG; COG2211; Bacteria.
DR HOGENOM; CLU_371281_0_0_12; -.
DR Proteomes; UP000004157; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR PANTHER; PTHR23526; INTEGRAL MEMBRANE TRANSPORT PROTEIN-RELATED; 1.
DR PANTHER; PTHR23526:SF2; MAJOR FACILITATOR SUPERFAMILY MFS_1; 1.
DR Pfam; PF03130; HEAT_PBS; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..297
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 751 AA; 82969 MW; A5448F223A1BD3E6 CRC64;
MSEELSAFRI KQGRRVYDIY NIINSLSFAL VTGNTITLYA LSLGANSTIV GLLNAFMYFC
YFAIPLGKLM VRKYTVIRTF AYAWFMRNLS LLPMLVIPLF FFAGNNFVAL NLLVLSVACF
NIFRGAGMIA NNPVIKILAP GKDRSSYIVR ISLTNNAATL IATLLLAGML WINISVTTYN
IATIIGMISG FIASALLLKL PDPEKEAEKG GEAQTPLQEP AEQHSFFTHA RDAFKDANFR
LFITAFFIVG FGIGMARPFI IVFAKEVYGT SDSLATIFTV CSSFGALIVG LIMRLVIDRI
GAKPMYIIFS SLALVTLIPA IIAPGLGTVS LAIVVLCLIS MITNMGFVGQ DNAAQAYFFA
MVPEEAIMDL SMLYYFVLGI TGGGGAILGG TILDFFKSLG FSNLESYRIF FIGIIVIIAI
GLLFQAKLLN LGSYRVFETL AVLFSPRDMK ALNLLHKLDS NQNLEAEQNI LKELGEIASS
VSADQLGSYL ESPRFSIRYG ALQALYSIEA LSSKNREDLL LELKSGAFTT ASSAARILGK
FKVQQAIPAL RTALDSEDYA LAGEAMLALA NLNDTYSQIK IGNMIANTDN PFLLLRGIQA
LETFGSISSL PLILDLLRQE NLPLHVEDEA LLALSSLMGI QNAFYYAFER YKNKQKAPNI
LLIDALDESF SLRKKHDEKL KNIVLQFIQD YQYDTEFVNW LIEYGDKRLG VRAALLIGVA
VDLDLINQEP FRFFICFWAA CIFRNPKLIE S
//
