ID E7NU71_TREPH Unreviewed; 491 AA.
AC E7NU71;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Peptidase Do {ECO:0000313|EMBL:EFW37895.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:EFW37895.1};
GN ORFNames=HMPREF9554_01617 {ECO:0000313|EMBL:EFW37895.1};
OS Treponema phagedenis F0421.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW37895.1, ECO:0000313|Proteomes:UP000004157};
RN [1] {ECO:0000313|EMBL:EFW37895.1, ECO:0000313|Proteomes:UP000004157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0421 {ECO:0000313|EMBL:EFW37895.1,
RC ECO:0000313|Proteomes:UP000004157};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW37895.1}.
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DR EMBL; AEFH01000138; EFW37895.1; -; Genomic_DNA.
DR AlphaFoldDB; E7NU71; -.
DR STRING; 162.TPHV1_80066; -.
DR eggNOG; COG0265; Bacteria.
DR HOGENOM; CLU_020120_1_0_12; -.
DR Proteomes; UP000004157; Unassembled WGS sequence.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 2.
DR Gene3D; 2.30.42.10; -; 2.
DR Gene3D; 2.40.10.120; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011782; Pept_S1C_Do.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR NCBIfam; TIGR02037; degP_htrA_DO; 1.
DR PANTHER; PTHR22939; SERINE PROTEASE FAMILY S1C HTRA-RELATED; 1.
DR PANTHER; PTHR22939:SF129; SERINE PROTEASE HTRA2, MITOCHONDRIAL; 1.
DR Pfam; PF13180; PDZ_2; 2.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 2.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EFW37895.1};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 283..353
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT ACT_SITE 133
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 163
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
FT ACT_SITE 239
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR611782-1"
SQ SEQUENCE 491 AA; 52673 MW; 392E87B34977F256 CRC64;
MTVSAAVVAV FLVLVSARCS TNRESADTVF ADSGAAEGIS KDTVSLLEGL QGAYRQVTSA
VLPAVVTLDV VETRKVRVQD PFSDGFPWFF FGNPENRDEK NEPKEREFRA EGLGSGVIVR
KTGKIYYVLT NYHVVGKAND IEVKHYDGRT FKGKLVGGDQ RKDIALVSFE TSDNNITVAK
LGNSDVAQVG DIVFAIGSPL GYSSSVTQGI ISAVGRFGGP GNTINDFIQT DAAINQGNSG
GPMVNIYGEV IGINSWIASS SGGSQGLGFS IPINNVKKDI DSFIQYGEIK YGWLGVQLIG
TDANTIAELG IPKNIDGALV AQIFLGSPAD KGGMKPGDYV TKLNGKTVKD INQLVRDIGN
LGKGQTASFV LMRNGKELSL NVKIDARDEK IVEDSAKLWP GVVPVPITDS IREQLKLKKN
ITGVIAANIQ NKSPAAIMGL KSGDVITAVN DTKIANIKEF YNVISQQTKE VWFDVLREGQ
TLSTIRFKLS K
//
