ID E7NWF2_TREPH Unreviewed; 502 AA.
AC E7NWF2;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Sigma-54 interaction domain protein {ECO:0000313|EMBL:EFW37108.1};
GN ORFNames=HMPREF9554_02416 {ECO:0000313|EMBL:EFW37108.1};
OS Treponema phagedenis F0421.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW37108.1, ECO:0000313|Proteomes:UP000004157};
RN [1] {ECO:0000313|EMBL:EFW37108.1, ECO:0000313|Proteomes:UP000004157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0421 {ECO:0000313|EMBL:EFW37108.1,
RC ECO:0000313|Proteomes:UP000004157};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW37108.1}.
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DR EMBL; AEFH01000206; EFW37108.1; -; Genomic_DNA.
DR RefSeq; WP_002700103.1; NZ_GL638098.1.
DR AlphaFoldDB; E7NWF2; -.
DR STRING; 162.TPHV1_10028; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_95_2_12; -.
DR Proteomes; UP000004157; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR PANTHER; PTHR32071:SF121; PTS-DEPENDENT DIHYDROXYACETONE KINASE OPERON REGULATORY PROTEIN-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00065; GAF; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 195..424
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 502 AA; 56065 MW; E1C21C6DCA919B58 CRC64;
MNLSTNIDAE KLNALIQISL LINSNYSDLN ALLEKIVQSA MDVVGGDAAS LLIVTADKKN
LRFEIALGPR GIEAKKILVG LNGIAGWVVK HSKSAIINDV QNDTRFDSSV QKTTGYVTRN
MLAVPMRIKT ECIGVIEVLN KADNQDFTLN DLEVLELFAT QTALAYQNAS NYKQSQEEII
RLQDQLTQEQ GYHTLIAESP IMLEKLAICK RIAVSDASVL ILGESGVGKE LIAEQIHLNS
DRAGEPFIRV NCAALPEGLL ESELFGHVRG AFTDAVADRK GRFETANKGT IFLDEIGEVP
LFVQAKLLRV LQDKTFEPVG SSKTFVADVR IIAATNRNIE KLVEEGTFRA DLYYRLNVLP
IYIPPLRQRI EDIPALANFF LKKFNKAVKK DFAGFTETAM SAMLAYHWPG NIREFENAVE
RACVVGTPPY ITEDALFFTT NKTFVENPED KTLKTAINVF KKQYILSVLE KNNWNQTSTA
EVLDIQRTYL SRLLKELDIK EK
//
