ID   E7S931_9STRE            Unreviewed;      1235 AA.
AC   E7S931;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Putative cross-wall-targeting lipoprotein signal {ECO:0000313|EMBL:EFV99947.1};
GN   ORFNames=HMPREF9421_0567 {ECO:0000313|EMBL:EFV99947.1};
OS   Streptococcus australis ATCC 700641.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888833 {ECO:0000313|EMBL:EFV99947.1, ECO:0000313|Proteomes:UP000002814};
RN   [1] {ECO:0000313|EMBL:EFV99947.1, ECO:0000313|Proteomes:UP000002814}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700641 {ECO:0000313|EMBL:EFV99947.1,
RC   ECO:0000313|Proteomes:UP000002814};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFV99947.1}.
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DR   EMBL; AEQR01000007; EFV99947.1; -; Genomic_DNA.
DR   AlphaFoldDB; E7S931; -.
DR   eggNOG; COG3266; Bacteria.
DR   HOGENOM; CLU_265996_0_0_9; -.
DR   Proteomes; UP000002814; Unassembled WGS sequence.
DR   Gene3D; 2.60.40.4300; -; 2.
DR   Gene3D; 3.10.20.470; -; 1.
DR   InterPro; IPR041558; MucBP_2.
DR   InterPro; IPR046776; Pectate_lyase_5.
DR   InterPro; IPR005877; YSIRK_signal_dom.
DR   NCBIfam; TIGR01168; YSIRK_signal; 1.
DR   Pfam; PF17965; MucBP_2; 1.
DR   Pfam; PF20585; Pectate_lyase_5; 1.
DR   Pfam; PF04650; YSIRK_signal; 1.
PE   4: Predicted;
KW   Lipoprotein {ECO:0000313|EMBL:EFV99947.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002814};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..41
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           42..1235
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003222013"
FT   DOMAIN          8..32
FT                   /note="YSIRK Gram-positive signal peptide"
FT                   /evidence="ECO:0000259|Pfam:PF04650"
FT   DOMAIN          940..1014
FT                   /note="Mucin binding"
FT                   /evidence="ECO:0000259|Pfam:PF17965"
FT   REGION          44..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1020..1041
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..112
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        113..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1022..1036
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1235 AA;  132548 MW;  9090D600934D19E8 CRC64;
     MDMKDIFNRR QRFSLRKYSI GVCSVLLGTA LFAAGSQTVL ADEVENPADS TSDVISSEAT
     SDKEIALSKP VTGESSAPTS YNVAAIVQPS VATDSQHEGD KEAGKEATAE PTETVSREAT
     GTSGFRNSGE VTSRVVSNWN GFVSALNDNS IQNITISGNV VATGDNGNTD NGRVNSVDRT
     VAINSQGRNV VIQGRNDQAS LDLLSNSLKF TGSSAWNLVF KNLQLATGNS KGPIDLSATT
     GANTVTFENV KSQGSSLYGG GGNTDVIVKG TTTSTVSDSY RVANGQTQYV QRNVGSAGHS
     VLRREANIHD AKSITVADGA SLTLNRSSQG DAINLAGGST VRVNDGASLT INMNTNNGTE
     SARYHNAGIF MEHGGTVVTG KDSKLTLNTS IGQAISLGMG RPADGLTHLD RWGGYGTGNA
     FRRNGKSSLT IGEHASFNFT GRDGLIFGNN ATFTTGSNSR VRFENKGRGT AIDFGDNSRV
     VFGKKSTNTF HSVGKGPKSG GGPSGSYNAY NYIGLNENGS ILVDDYATFR VQMDNRGANP
     WDDVINLDSK HGRKDQPLFQ ANKGSIVDVR DDNTDYYAEL ISVPLGSSTN VVFQFNNPLY
     VSLMRYTNSE GRSAGEITGK LPFGIAQGNN PEQIGHGNIL YISNGSKVSG NHIEFNGPTG
     TRVNRGAGTY TVYSLNKDGR DVVSKNKMSS VWTDIQGGAM SIAGFKPGGK AEINPSSSTS
     VQTGSSSGGV LATDKTYGID PVTANRQNIW VSNGTSINPH ATHTNTIRYV YEDGTPVLDA
     NGKPKVVVQS SDWKRLLEVA IDQDQFKNVL KNSSVANGDE FLAAYGKTEY VVRDIDGDGI
     GDTGWRLAGT KNSKATYDTV VSPELQGYKA EILSSNVPGL AVGTKASRVS VTFNPSEIKD
     EIVISQGGRR TVSETYWRNI VDNVELTNYE TVVVYKQDKQ KASVKYVNVT SNIELAKDEM
     EGQSGSLIDY STVDRITTYK KAGYKLIEDG FTNATDKHFD TNVSVDQEFV VTLEERIEPV
     TPQDPKPVPG IPVTPEDPAN WPKEVKDMKE LERTATQTIR FREEESGKEV FKTILRKITF
     ERTAYVNLVT GNITYSSWRI GKVVDQDGPV QPVNSNTANR VNVAPNTGEV RSLSARVRRS
     VSTETTPVAD PATVVEEPSS APKVEAKEER MPVEPAVRTV ESKPVETPKV LKIPKVQPEA
     VTVATRKASA TLNKRVYGAK PVVTRGRSSR RPPKI
//