ID E8JUX3_STRCR Unreviewed; 449 AA.
AC E8JUX3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=Trk system potassium uptake protein TrkA {ECO:0000256|ARBA:ARBA00017378};
GN Name=trkA {ECO:0000313|EMBL:EFX52869.1};
GN ORFNames=HMPREF9422_0971 {ECO:0000313|EMBL:EFX52869.1};
OS Streptococcus cristatus ATCC 51100.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=889201 {ECO:0000313|EMBL:EFX52869.1, ECO:0000313|Proteomes:UP000002829};
RN [1] {ECO:0000313|EMBL:EFX52869.1, ECO:0000313|Proteomes:UP000002829}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51100 {ECO:0000313|EMBL:EFX52869.1,
RC ECO:0000313|Proteomes:UP000002829};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFX52869.1}.
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DR EMBL; AEVC01000011; EFX52869.1; -; Genomic_DNA.
DR RefSeq; WP_005590884.1; NZ_LS483383.1.
DR AlphaFoldDB; E8JUX3; -.
DR GeneID; 48422933; -.
DR eggNOG; COG0569; Bacteria.
DR HOGENOM; CLU_046525_0_1_9; -.
DR Proteomes; UP000002829; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0015079; F:potassium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 2.
DR InterPro; IPR006036; K_uptake_TrkA.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR InterPro; IPR003148; RCK_N.
DR PANTHER; PTHR43833; POTASSIUM CHANNEL PROTEIN 2-RELATED-RELATED; 1.
DR PANTHER; PTHR43833:SF5; TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKA; 1.
DR Pfam; PF02080; TrkA_C; 2.
DR Pfam; PF02254; TrkA_N; 2.
DR PRINTS; PR00335; KUPTAKETRKA.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 2.
DR PROSITE; PS51202; RCK_C; 2.
DR PROSITE; PS51201; RCK_N; 2.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:EFX52869.1}.
FT DOMAIN 2..128
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 140..222
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
FT DOMAIN 227..348
FT /note="RCK N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51201"
FT DOMAIN 368..449
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 449 AA; 50384 MW; 82C2ED00798A102A CRC64;
MKIIVVGSGK VGAALCRSLV AEKHDVVLIE QNEAVLNHIT KRYDIMGIVG NGANFKILEQ
ADVAHCDIFI AMTEQDEVNM VSAVLAKKMG AKETIVRVRN PEYSNAYFKE KNILGFSLMV
NPELLAARYI ANIIDFPNAL SLEHFANGRV TLMEFKIKPE SHLCQMNLSQ FRKHFPHVII
CAIEREGKLS IPDGDFTLQP SDKIFLTGNR SEIVRFHNKI RPRVIKSLMI IGAGKIAYYL
LNILKNSKIE LKVVEINRQR AEFFSQEFPE LYVVNGDGTA KDILLEERAA HYDAIATLTG
VDEENIITSM FLNNLGVQKN ITKINRTSLL EIIDNQDFAS IVTPKGIAVD TIMHFIRGRN
NAQFSSLEAL HHVANGQIET LQFQINEGNK MIEQPLSQLK LRSGVLIAAI IRQGVAIFPS
GDDYLEVGDK IIVTTLIQNI DKIYDLLER
//
