ID   E8K4L3_STRPA            Unreviewed;       254 AA.
AC   E8K4L3;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Integrase core domain protein {ECO:0000313|EMBL:EFX39280.1};
GN   ORFNames=HMPREF8577_0498 {ECO:0000313|EMBL:EFX39280.1};
OS   Streptococcus parasanguinis ATCC 903.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888048 {ECO:0000313|EMBL:EFX39280.1, ECO:0000313|Proteomes:UP000005490};
RN   [1] {ECO:0000313|EMBL:EFX39280.1, ECO:0000313|Proteomes:UP000005490}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 903 {ECO:0000313|EMBL:EFX39280.1,
RC   ECO:0000313|Proteomes:UP000005490};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFX39280.1}.
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DR   EMBL; AEVE01000020; EFX39280.1; -; Genomic_DNA.
DR   AlphaFoldDB; E8K4L3; -.
DR   eggNOG; COG2801; Bacteria.
DR   HOGENOM; CLU_027402_4_3_9; -.
DR   Proteomes; UP000005490; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR048020; Transpos_IS3.
DR   NCBIfam; NF033516; transpos_IS3; 1.
DR   PANTHER; PTHR46889; TRANSPOSASE INSF FOR INSERTION SEQUENCE IS3B-RELATED; 1.
DR   PANTHER; PTHR46889:SF1; TRANSPOSASE INSO FOR INSERTION SEQUENCE ELEMENT IS911B-RELATED; 1.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF00665; rve; 1.
DR   Pfam; PF13333; rve_2; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   4: Predicted;
FT   DOMAIN          88..253
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50994"
SQ   SEQUENCE   254 AA;  29811 MW;  4A2D14DD4E566831 CRC64;
     MKQLDKPDKD QGLKAEIQSI FTEHKGNYGY RRIHLELRNH GFLVNHKRVQ RLMNVLNLQA
     RIRQKRKYSS HKGDIGKKAD NLIQRQFEAS KPMEKCYTDV TEFAIPASTQ KLYLSPVLDG
     FNSEIVAYNL STSPNLEQVK AMLDQAFTEN HYTNTILHSD QGWQYQHQYY HRFLEDKGIQ
     PSMSRKGNSP DNGMMESFFG ILKSEMFYGY EKTFQSLEQL EQAIVDYIDY YNNKRIKVKL
     KGLSPVQYRT KSFV
//