ID E8R0B5_ISOPI Unreviewed; 448 AA.
AC E8R0B5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=RNA polymerase alpha subunit domain protein {ECO:0000313|EMBL:ADV62242.1};
GN OrderedLocusNames=Isop_1658 {ECO:0000313|EMBL:ADV62242.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV62242.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV62242.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
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DR EMBL; CP002353; ADV62242.1; -; Genomic_DNA.
DR AlphaFoldDB; E8R0B5; -.
DR STRING; 575540.Isop_1658; -.
DR KEGG; ipa:Isop_1658; -.
DR eggNOG; COG0202; Bacteria.
DR eggNOG; COG0457; Bacteria.
DR HOGENOM; CLU_606697_0_0_0; -.
DR InParanoid; E8R0B5; -.
DR Proteomes; UP000008631; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR011260; RNAP_asu_C.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR44858; TETRATRICOPEPTIDE REPEAT PROTEIN 6; 1.
DR PANTHER; PTHR44858:SF1; UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE SPINDLY-RELATED; 1.
DR Pfam; PF03118; RNA_pol_A_CTD; 2.
DR Pfam; PF00515; TPR_1; 1.
DR Pfam; PF13432; TPR_16; 1.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF47789; C-terminal domain of RNA polymerase alpha subunit; 2.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008631};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 158..191
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 226..259
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 286..347
FT /note="RNA polymerase alpha subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03118"
FT DOMAIN 378..440
FT /note="RNA polymerase alpha subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03118"
SQ SEQUENCE 448 AA; 50285 MW; 590086B14133CD9A CRC64;
MATSAMKFTT DVRMLLDRDP FDQSAVADLL EALSRDPSRY STLREAVAAM QTKHAQSMSP
DIHLRLGVAQ VLLGRYSLGI GHLEKAGEVG LAHYYRGLAL ECQQRFREAA QAFGAAAELG
YLADKSQLHR AGALRRLGES DQARELLDKL KDRAQSIAEY HHQRGCLLVE EGLMAEAAEA
FETALKLDKD HSGALFQLAY LNDLAGNDET ARELYQRCVQ KPPVPLGALI NLGILYEDEE
KYREAEQCFR RVLDIYPNHP RARLYLKDVR ASKEMYYDEE AERRYDHLRQ VLEIPVTDFE
LSVRSRNCLK KMGIRTLGDL TRITESQLLS SKNFGETSLT EIKAMMEAKS LRLGMAIENG
EAGGFKVAVE PVDEPISPEE RAKLAMPITE LNLSVRARKC MNKLGITTVG ELIAHTQDQL
LECKNFGVTS LNEVRDKLSE LGLKLKND
//
