ID E8R6D6_ISOPI Unreviewed; 667 AA.
AC E8R6D6;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=UspA domain-containing protein {ECO:0000313|EMBL:ADV61837.1};
GN OrderedLocusNames=Isop_1251 {ECO:0000313|EMBL:ADV61837.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV61837.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV61837.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP002353; ADV61837.1; -; Genomic_DNA.
DR RefSeq; WP_013564126.1; NC_014962.1.
DR AlphaFoldDB; E8R6D6; -.
DR STRING; 575540.Isop_1251; -.
DR KEGG; ipa:Isop_1251; -.
DR eggNOG; COG0531; Bacteria.
DR eggNOG; COG0589; Bacteria.
DR HOGENOM; CLU_406458_0_0_0; -.
DR InParanoid; E8R6D6; -.
DR OrthoDB; 251655at2; -.
DR Proteomes; UP000008631; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd00293; USP_Like; 1.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR47704; POTASSIUM TRANSPORTER KIMA; 1.
DR PANTHER; PTHR47704:SF1; POTASSIUM TRANSPORTER KIMA; 1.
DR Pfam; PF13520; AA_permease_2; 1.
DR Pfam; PF00582; Usp; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008631};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 334..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 534..661
FT /note="UspA"
FT /evidence="ECO:0000259|Pfam:PF00582"
SQ SEQUENCE 667 AA; 71104 MW; 0C010E90D842CA12 CRC64;
MSGFGERPRE LKWYHAGPIL FGDWGTSRLY VLGLAFAFNG RASFWMVAAM SLVLIAVGWC
YTIACRLFPD GGGVYSSAQQ RSQLLAVFGG LLLCADYVVT ASLSCLEAFH YLGIKDYTIL
GILPVDAALA ALGILAIGAV NVLGPTKTGT AAMIVAMATV VFTLIIGVAC LPYLGNMVVE
SPFKEGPGRA WVGFTEIILA LSGVEAIANM TGVMVQPVGR TAKRAILPVM TEIVLLNLIL
CAAMLTLADD VLYRLDPETG GLVPAHTGDM IKVIAETYVG PAFAAASGVC FAALLFSAVN
TAVGALVSVL FMLSRDRELP EAFGRLNRFG MPKLPLVIAA VVPAVVVVVF PYVESLGGLY
AIGIVGAIGI NLGSIATNRA LDIRRGERIL MAGVTLLLIA IEITIVFDKP DARSFALVVL
AAGLSARLGT MAIHPAVPLG QLTRRGYVIS GVVLTLAVLF VEIAFHDTLG GFAVSAVLVC
VLAGASYKVQ QFRPEILAYR SRRVEVELGP DGKPLETRPK RLMMVPGGYK PKARVMVATQ
GNPRLLKFAF EEAKNRHAEL QILFLRHLAV TPMGLVEPPK LDEDEDALKL FEQVREQAKK
EGVPIRLLYG VARDIPDAIL DMAVTHGADL LMLGATRRGT LWKAMKGDVI SGVAEQLPES
VGLLLVA
//
