ID E8RAN5_DESM0 Unreviewed; 157 AA.
AC E8RAN5;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Large ribosomal subunit protein uL22 {ECO:0000256|HAMAP-Rule:MF_01331};
GN Name=rpl22 {ECO:0000256|HAMAP-Rule:MF_01331};
GN OrderedLocusNames=Desmu_1174 {ECO:0000313|EMBL:ADV65471.1};
OS Desulfurococcus mucosus (strain ATCC 35584 / DSM 2162 / JCM 9187 / O7/1).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Desulfurococcus.
OX NCBI_TaxID=765177 {ECO:0000313|EMBL:ADV65471.1, ECO:0000313|Proteomes:UP000001068};
RN [1] {ECO:0000313|Proteomes:UP000001068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35584 / DSM 2162 / JCM 9187 / O7/1
RC {ECO:0000313|Proteomes:UP000001068};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G.,
RA Chertkov O., Held B., Brettin T., Detter J.C., Tapia R., Han C., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Wirth R., Bilek Y., Hader T., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Desulfurococcus mucosus DSM 2162.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV65471.1, ECO:0000313|Proteomes:UP000001068}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35584 / DSM 2162 / JCM 9187 / O7/1
RC {ECO:0000313|Proteomes:UP000001068};
RX PubMed=21677854; DOI=10.4056/sigs.1644004;
RA Wirth R., Chertkov O., Held B., Lapidus A., Nolan M., Lucas S., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Ioanna P., Ivanova N., Mavromatis K., Mikhailova N., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Bilek Y., Hader T., Rohde M., Spring S., Sikorski J., Goker M., Woyke T.,
RA Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C.,
RA Klenk H.P.;
RT "Complete genome sequence of Desulfurococcus mucosus type strain (O7/1).";
RL Stand. Genomic Sci. 4:173-182(2011).
CC -!- FUNCTION: The globular domain of the protein is located near the
CC polypeptide exit tunnel on the outside of the subunit, while an
CC extended beta-hairpin is found that lines the wall of the exit tunnel
CC in the center of the 70S ribosome. {ECO:0000256|HAMAP-Rule:MF_01331}.
CC -!- FUNCTION: This protein binds specifically to 23S rRNA. It makes
CC multiple contacts with different domains of the 23S rRNA in the
CC assembled 50S subunit and ribosome. {ECO:0000256|HAMAP-Rule:MF_01331,
CC ECO:0000256|RuleBase:RU004007}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000256|HAMAP-
CC Rule:MF_01331, ECO:0000256|RuleBase:RU004007}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL22 family.
CC {ECO:0000256|ARBA:ARBA00009451, ECO:0000256|HAMAP-Rule:MF_01331,
CC ECO:0000256|RuleBase:RU004005}.
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DR EMBL; CP002363; ADV65471.1; -; Genomic_DNA.
DR RefSeq; WP_013562693.1; NC_014961.1.
DR AlphaFoldDB; E8RAN5; -.
DR STRING; 765177.Desmu_1174; -.
DR GeneID; 10153889; -.
DR KEGG; dmu:Desmu_1174; -.
DR eggNOG; arCOG04098; Archaea.
DR HOGENOM; CLU_083987_0_2_2; -.
DR OrthoDB; 314984at2157; -.
DR Proteomes; UP000001068; Chromosome.
DR GO; GO:0015934; C:large ribosomal subunit; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR CDD; cd00336; Ribosomal_L22; 1.
DR Gene3D; 3.90.470.10; Ribosomal protein L22/L17; 1.
DR HAMAP; MF_01331_A; Ribosomal_L22_A; 1.
DR InterPro; IPR001063; Ribosomal_uL22.
DR InterPro; IPR018260; Ribosomal_uL22_CS.
DR InterPro; IPR005721; Ribosomal_uL22_euk/arc.
DR InterPro; IPR036394; Ribosomal_uL22_sf.
DR NCBIfam; TIGR01038; uL22_arch_euk; 1.
DR PANTHER; PTHR11593; 60S RIBOSOMAL PROTEIN L17; 1.
DR PANTHER; PTHR11593:SF10; 60S RIBOSOMAL PROTEIN L17; 1.
DR Pfam; PF00237; Ribosomal_L22; 1.
DR SUPFAM; SSF54843; Ribosomal protein L22; 1.
DR PROSITE; PS00464; RIBOSOMAL_L22; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001068};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_01331};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_01331};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_01331,
KW ECO:0000256|RuleBase:RU004007};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01331,
KW ECO:0000256|RuleBase:RU004007}.
SQ SEQUENCE 157 AA; 18226 MW; 4603A9DAC51CDBD1 CRC64;
MPTWHYSVKY RDESKIAKAV RYDIPVSVKY MREIAYTLKG MRLSDAIRFL EDVIKMKQAV
PFRRYNGKLS HKRGLADRFK WPIGRYPVKG AKYALEVLRN VEANAEEKGL SKERLVIVHI
AAHKGITLKR YMPRAFGRAT PKFRRMSNLE VVVGEVG
//
