ID E8TG60_MESCW Unreviewed; 600 AA.
AC E8TG60;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Cl-channel voltage-gated family protein {ECO:0000313|EMBL:ADV12330.1};
GN OrderedLocusNames=Mesci_3206 {ECO:0000313|EMBL:ADV12330.1};
OS Mesorhizobium ciceri biovar biserrulae (strain HAMBI 2942 / LMG 23838 /
OS WSM1271).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Phyllobacteriaceae; Mesorhizobium.
OX NCBI_TaxID=765698 {ECO:0000313|EMBL:ADV12330.1, ECO:0000313|Proteomes:UP000007471};
RN [1] {ECO:0000313|Proteomes:UP000007471}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HAMBI 2942 / LMG 23838 / WSM1271
RC {ECO:0000313|Proteomes:UP000007471};
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Nandasena K., Reeve W.G., Howieson J.G., O'Hara G.,
RA Tiwari R.P., Woyke T.;
RT "Complete sequence of chromosome of Mesorhizobium ciceri bv. biserrulae
RT WSM1271.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002447; ADV12330.1; -; Genomic_DNA.
DR RefSeq; WP_013531013.1; NC_014923.1.
DR RefSeq; YP_004142380.1; NC_014923.1.
DR AlphaFoldDB; E8TG60; -.
DR STRING; 765698.Mesci_3206; -.
DR KEGG; mci:Mesci_3206; -.
DR PATRIC; fig|765698.3.peg.3701; -.
DR eggNOG; COG0038; Bacteria.
DR eggNOG; COG0517; Bacteria.
DR HOGENOM; CLU_015263_5_0_5; -.
DR OrthoDB; 9767361at2; -.
DR Proteomes; UP000007471; Chromosome.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 452..511
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 600 AA; 63400 MW; 8A46347A7E33639C CRC64;
MKTHHSNPEH LRDFTTDPRV LLVAAIAVVV ATAGLFAGIA LLKLIRLATN IAYFGQFSLA
DLKLENTPLG LAAVLVPVIG ALIIGLMARY GSEKIRGHGI PEAIEAILLG RSKLDAKVAI
LKPLSSAISI GSGGPFGAEG PIIMTGGAIG SLIAQMLPVS DNERKTLLVA GAAAGMTTVF
GTPIAAIMLA VELLLFEWTP RSFIPVAVAA VIAEVERTML HLPGPIFPFQ GGMEVSFVGL
AGWVAIGVCA GLLSGLLTQM VYACEDGFQK LPIHWMWWPM LGGLVVGIGG LIEPHALGVG
YDNITDMLDG RTVATAALLL LVVKAIIWSV ALGSGTSGGV LAPLLIMGGA MGAVLAGVLP
AADPGFWALL AMAATMGGTM RAPLTATFFA VELTGNTHML VPLIAACAAA HAVTVLLMKR
SILTEKIARR GHHLVREYRV DPFALTRVRE VMTSQVESVP ATMTLHGAAA FLTAPETRHP
SFPVVDENGQ VLGLIDPPAI LRWRRAGTHR TTTLGALLAG SKVTLAYPDE YLEGLSDKLL
MANVSHLPVV TREGSLLVGY VGWKDLMRVR SRKQAEERER STLLGFGTRR RKKDDAVESL
//
