ID E8U8J1_DEIML Unreviewed; 917 AA.
AC E8U8J1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ADV67380.1};
DE Flags: Precursor;
GN OrderedLocusNames=Deima_1731 {ECO:0000313|EMBL:ADV67380.1};
OS Deinococcus maricopensis (strain DSM 21211 / LMG 22137 / NRRL B-23946 /
OS LB-34).
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=709986 {ECO:0000313|EMBL:ADV67380.1, ECO:0000313|Proteomes:UP000008635};
RN [1] {ECO:0000313|EMBL:ADV67380.1, ECO:0000313|Proteomes:UP000008635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34
RC {ECO:0000313|Proteomes:UP000008635};
RX PubMed=21677853; DOI=10.4056/sigs.1633949;
RA Pukall R., Zeytun A., Lucas S., Lapidus A., Hammon N., Deshpande S.,
RA Nolan M., Cheng J.F., Pitluck S., Liolios K., Pagani I., Mikhailova N.,
RA Ivanova N., Mavromatis K., Pati A., Tapia R., Han C., Goodwin L., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Brambilla E.M., Rohde M., Goker M., Detter J.C., Woyke T., Bristow J.,
RA Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Deinococcus maricopensis type strain (LB-
RT 34).";
RL Stand. Genomic Sci. 4:163-172(2011).
RN [2] {ECO:0000313|Proteomes:UP000008635}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 21211 / LMG 22137 / NRRL B-23946 / LB-34
RC {ECO:0000313|Proteomes:UP000008635};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Goodwin L., Pitluck S., Kyrpides N.,
RA Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G., Zeytun A.,
RA Detter J.C., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Pukall R., Gehrich-Schroeter G.,
RA Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Deinococcus maricopensis DSM 21211.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002454; ADV67380.1; -; Genomic_DNA.
DR RefSeq; WP_013556885.1; NC_014958.1.
DR AlphaFoldDB; E8U8J1; -.
DR STRING; 709986.Deima_1731; -.
DR KEGG; dmr:Deima_1731; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_317553_0_0_0; -.
DR OrthoDB; 9759607at2; -.
DR Proteomes; UP000008635; Chromosome.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008635}.
FT DOMAIN 384..421
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 529..658
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 667..916
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 917 AA; 99010 MW; 7891045E21331643 CRC64;
MPNRLQSRVR PPRATSTPPQ AVNLSFARAR TLSTLAGALT QARTADEIRR AVLTFTPPAV
LAYAINLMTL GDDQHVHLIG QQGYALHVMQ PYAHLPLTQP APSTDVIRSG EALYLTRADL
HARYPDITWD ERTHAIAALP LAAAGTPFGA MVVSFDDPGV PSAETRAFLE GVAGLCAVAL
ERAAWTERAE RAIREQAEER AWLTNLADAS ARLADARGVP DTLSVSADVA LTLGDWTLLS
LPGPDGTLHA RAIAHTDPVR AEGARAHLRA AVLPTEPLPG LTDAYRSARP VLHSDVSPEA
LAALDLPDAA QAVLRQLRVH SVLHLPLLTH GRAIGVLTVL NETRPFEDGQ RLYAQNLAGR
IAAALDNALL YQDVVERASG QEAVMEALTE GLLILDEDGT VILTNPSAPQ LLGLSPTSMI
GVPIADLVGA TLDLDGAPTP VTAEDIVGLP NALDLVRGVD TPSGRRWFKL GARPLQQGGR
QLTVCTFADV TDAIERERRL VHLAHHDDLT GLPNRRALRE HLQRALHNGP CSIALLDLQG
FKGVNDTYGH DFGDQLLIAA ARALQAAAPP GAILARPGGD EFALLLCGPH DWAATWERWL
DALSVPLRVG GTAWRTTVNA GYAVAPEDGT DVRNLLAAAD LAQRAAKHAL QPLAPFRAEY
RQAIERRTDL EQHLRVALQR HELRVALQPI LHVHDLQVMG YEALARWIRP DGQFVSPAEF
IAVAESTDLI HPLGRQMAHL ALRALTRPGV PEHTCVTINV SAVQLGRAHY HEELTAQLRA
ANVPPNRLIL EVTESAVIND QPTARRNLLA LAETGVHIAL DDFGHGYSSL KLLQMLPFTI
VKIDAELMRS GMRDPTFLRA IIQVASATGA SVVAEGVETD EQLRTLRDLN VPLAQGYLLG
RPQLVEFPPD TLTKEAP
//
