ID E8WZN4_GRATM Unreviewed; 339 AA.
AC E8WZN4;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Isocitrate dehydrogenase (NAD(+)) {ECO:0000313|EMBL:ADW70008.1};
DE EC=1.1.1.41 {ECO:0000313|EMBL:ADW70008.1};
GN OrderedLocusNames=AciX9_2985 {ECO:0000313|EMBL:ADW70008.1};
OS Granulicella tundricola (strain ATCC BAA-1859 / DSM 23138 / MP5ACTX9).
OC Bacteria; Acidobacteriota; Terriglobia; Terriglobales; Acidobacteriaceae;
OC Granulicella.
OX NCBI_TaxID=1198114 {ECO:0000313|Proteomes:UP000000343};
RN [1] {ECO:0000313|Proteomes:UP000000343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MP5ACTX9 {ECO:0000313|Proteomes:UP000000343};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Pagani I., Rawat S.R., Mannisto M.,
RA Haggblom M.M., Woyke T.;
RT "Complete sequence of chromosome of Acidobacterium sp. MP5ACTX9.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
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DR EMBL; CP002480; ADW70008.1; -; Genomic_DNA.
DR RefSeq; WP_013581322.1; NC_015064.1.
DR AlphaFoldDB; E8WZN4; -.
DR STRING; 1198114.AciX9_2985; -.
DR PaxDb; 1198114-AciX9_2985; -.
DR KEGG; acm:AciX9_2985; -.
DR eggNOG; COG0473; Bacteria.
DR HOGENOM; CLU_031953_0_1_0; -.
DR OrthoDB; 9806254at2; -.
DR Proteomes; UP000000343; Chromosome.
DR GO; GO:0004449; F:isocitrate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR PANTHER; PTHR11835:SF34; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:ADW70008.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000343}.
FT DOMAIN 5..333
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 339 AA; 36424 MW; 30FD743401A1BF83 CRC64;
MPTHKITLIP GDGIGPEVTA ATVKILEAAG KITGASFEWH THNAGADAFA KTGEYIPQSL
YDSVKENKVA LKGPVTTPIG GGFTSINVTL RKKFDLYSNF RPVKSLPGIK TNYPNLDLVI
FRENTEDLYA GLEVMINPDI AQSLKIITRK GSLRIAKSAF EYARRHGRKK VHAIHKANIM
KLSDGLFLKC CKEVAAEYPE ITYAEHIVDN TCMQLVMNPF QYDIILTENL YGDILSDLCS
GLIGGLGLVP GANIGVDASI FEAVHGSAPD IAGQDKANPT ALLQSAVLML HHLEETATAD
LIQKALERVY AEGKTLTRDI GGTAGTTAFS DAVVAALSA
//
