ID E8XAK3_SALT4 Unreviewed; 547 AA.
AC E8XAK3;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:ADX18940.1};
GN OrderedLocusNames=STM474_3303 {ECO:0000313|EMBL:ADX18940.1};
OS Salmonella typhimurium (strain 4/74).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=909946 {ECO:0000313|EMBL:ADX18940.1, ECO:0000313|Proteomes:UP000008978};
RN [1] {ECO:0000313|EMBL:ADX18940.1, ECO:0000313|Proteomes:UP000008978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4/74 {ECO:0000313|Proteomes:UP000008978};
RX PubMed=21478351; DOI=10.1128/JB.00394-11;
RA Richardson E.J., Limaye B., Inamdar H., Datta A., Manjari K.S.,
RA Pullinger G.D., Thomson N.R., Joshi R.R., Watson M., Stevens M.P.;
RT "Genome sequences of Salmonella enterica serovar typhimurium, Choleraesuis,
RT Dublin, and Gallinarum strains of well- defined virulence in food-producing
RT animals.";
RL J. Bacteriol. 193:3162-3163(2011).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
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DR EMBL; CP002487; ADX18940.1; -; Genomic_DNA.
DR RefSeq; WP_001238434.1; NC_016857.1.
DR AlphaFoldDB; E8XAK3; -.
DR SMR; E8XAK3; -.
DR KEGG; seb:STM474_3303; -.
DR PATRIC; fig|909946.3.peg.3387; -.
DR HOGENOM; CLU_000445_107_16_6; -.
DR Proteomes; UP000008978; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR InterPro; IPR004091; Chemotax_Me-accpt_rcpt_Me-site.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR003122; Tar_rcpt_lig-bd.
DR PANTHER; PTHR43531:SF5; METHYL-ACCEPTING CHEMOTAXIS PROTEIN II; 1.
DR PANTHER; PTHR43531; PROTEIN ICFG; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR Pfam; PF02203; TarH; 1.
DR PRINTS; PR00260; CHEMTRNSDUCR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR PROSITE; PS00538; CHEMOTAXIS_TRANSDUC_1; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Transducer {ECO:0000256|PROSITE-ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..264
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 269..498
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 515..547
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 487..514
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 547 AA; 58898 MW; EF186C4AF102E581 CRC64;
MRLLQNFTIR MVMLTILGLF CLLWSGVGLY SVHALSEVSE GNDIDRHLVR QMTVLSQGND
QYFRFVTRLS RAMDVKIGGG TPDFAPARQS LENMRQKLEE MKALSPGPMN PDISREVLSN
WQALLEKGVV PQMQLAQQGS LTAWSEHAST VTPALSRAFG ASAERFSHEA GAMLDNTRVM
VDGKTYTIRI LLITAVILGI AILIFTDRYL VAMMVKPLER IRQQFQRIAQ GDLSQPIEAL
GRNCVGRLVP LLRAMQDSLR EAVSTIRAGS DNIWRGATEI STGNNDLSSR TEEQAAALEE
TAASMEQLTA TVKMNAEHAR QASQLADAAS LTAGKGGELV SDVVETMNGI SASSQQIAEI
TTVINSIAFQ TNILALNAAV EAARAGEQGR GFAVVAGEVR NLASRSAGAA KEIEALIGES
VRRVAQGAQL VQETGATMDA ILRGVTEVTT IMKQIASASE EQSKGISQVG VAITQMDSVT
QQNAALVEQV SAAAAALERQ TEDLQRSVQQ FRLSASEPQQ RVTAKAAPGV QRMASAPAQS
TDEWVSF
//
