ID E9D8H7_COCPS Unreviewed; 638 AA.
AC E9D8H7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Carnitine acetyl transferase {ECO:0000313|EMBL:EFW17686.1};
GN ORFNames=CPSG_06129 {ECO:0000313|EMBL:EFW17686.1};
OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=443226 {ECO:0000313|Proteomes:UP000002497};
RN [1] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
RN [2] {ECO:0000313|Proteomes:UP000002497}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 757 / Silveira {ECO:0000313|Proteomes:UP000002497};
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., Gardner M.J.,
RA Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., Koehrsen M., Alvarado L.,
RA Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Jen D., Larson L., Mehta T., Neiman D., Park D., Pearson M.,
RA Richards J., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Walk T., White J., Yandava C., Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Coccidioides posadasii strain Silveira.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232, ECO:0000256|RuleBase:RU003801}.
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DR EMBL; GL636494; EFW17686.1; -; Genomic_DNA.
DR STRING; 443226.E9D8H7; -.
DR VEuPathDB; FungiDB:CPSG_06129; -.
DR VEuPathDB; FungiDB:D8B26_000355; -.
DR eggNOG; KOG3717; Eukaryota.
DR HOGENOM; CLU_013513_5_1_1; -.
DR OMA; MAMSSYE; -.
DR Proteomes; UP000002497; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589:SF115; CARNITINE O-ACETYLTRANSFERASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002497};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003801}.
FT DOMAIN 61..614
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
SQ SEQUENCE 638 AA; 71899 MW; 9B99A1231019C70F CRC64;
MFPAAARGRL VALGRASLPR PARTPVITMA ARRANSSVPA GYTEDLSKGR MLRFEDSLPQ
LPVPTLEETG KKYLKSLHPL LSAEEFKRSQ KAVEAFVKPG GEGETLQKRL LAKAADPKVQ
NWLYDWWNHA AYLGYRDPVV PYVSYFYSYR DDRNRRDPAK RAAAITTSVL EFKKQVDDGS
LEPEYLRKEP MAMSSYEYMF NCCRIPAEGA DYPQKYPAQG NEHIVVMRKN QIFKVQTHLN
GEQLNTSELQ QQFEKILKNA ERVPAVGALT SENRDFWTAA RKKLLAADPA NADALKTIES
ASFVVCLDDT APVTLEERAH VYWHGDGANR WFDKPLTFIV NDNGTAGFLG EHSMMDGTPT
HRLNDYVNNL IFNNRLDYSN PSVRSNLPEP QPVNFNLDSA VLEDITTAQK DFASVIGKHE
LRVQAFQAYG KGLIKKFKCS PDAYVQMLIQ LAYFKMYGKN RPTYESASTR KFKQGRTETT
RTVSDESVAF CKAHCDPAVP REETAKLFRA ALAAHTKYIA DASIGKGVDR HLFGLKQLIQ
KGEKVPALYE DPAYGYSGSW YLSTSQLSSE YFNGYGWSQV IDDGFGIAYM INENSLQFNI
VCKKLGADRM SFYLNEAACE VRDLLMPDLL AQQEKAKL
//
