ID E9DW13_METAQ Unreviewed; 214 AA.
AC E9DW13;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=CHD5 domain protein {ECO:0000313|EMBL:EFY92210.1};
GN Name=GET1 {ECO:0000256|HAMAP-Rule:MF_03113};
GN ORFNames=MAC_01811 {ECO:0000313|EMBL:EFY92210.1};
OS Metarhizium acridum (strain CQMa 102).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN [1] {ECO:0000313|EMBL:EFY92210.1, ECO:0000313|Proteomes:UP000002499}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY92210.1,
RC ECO:0000313|Proteomes:UP000002499};
RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA Wang C.;
RT "Genome sequencing and comparative transcriptomics of the model
RT entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL PLoS Genet. 7:E1001264-E1001264(2011).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004477}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004477}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the WRB/GET1 family.
CC {ECO:0000256|ARBA:ARBA00010799, ECO:0000256|HAMAP-Rule:MF_03113}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_03113}.
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DR EMBL; GL698477; EFY92210.1; -; Genomic_DNA.
DR RefSeq; XP_007808151.1; XM_007809960.1.
DR AlphaFoldDB; E9DW13; -.
DR STRING; 655827.E9DW13; -.
DR GeneID; 19246122; -.
DR KEGG; maw:MAC_01811; -.
DR eggNOG; KOG4253; Eukaryota.
DR HOGENOM; CLU_089418_1_0_1; -.
DR InParanoid; E9DW13; -.
DR OMA; AEWIISF; -.
DR OrthoDB; 1421963at2759; -.
DR Proteomes; UP000002499; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043529; C:GET complex; IEA:InterPro.
DR GO; GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IEA:InterPro.
DR Gene3D; 1.10.287.660; Helix hairpin bin; 1.
DR HAMAP; MF_03113; Get1; 1.
DR InterPro; IPR028945; Get1.
DR InterPro; IPR027538; Get1_fungi.
DR InterPro; IPR029012; Helix_hairpin_bin_sf.
DR PANTHER; PTHR42650:SF1; GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1; 1.
DR PANTHER; PTHR42650; TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB; 1.
DR Pfam; PF04420; CHD5; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|HAMAP-Rule:MF_03113};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824, ECO:0000256|HAMAP-
KW Rule:MF_03113};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_03113};
KW Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_03113};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_03113};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_03113}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..214
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003238227"
FT TOPO_DOM 1..3
FT /note="Lumenal"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03113"
FT TOPO_DOM 172..214
FT /note="Cytoplasmic"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03113"
FT REGION 186..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..100
FT /evidence="ECO:0000256|HAMAP-Rule:MF_03113"
FT COMPBIAS 200..214
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 214 AA; 24513 MW; ED4005B4D62B66F6 CRC64;
MTILFLIFAV EVLAQFITAV GAAQINNLIW TLINYLPVST SKAAAEQRKL QAEYLKVRRE
LNATSSQDEF AKWAKLRRQH DKLLEKLDAA KKAMEASRAR FDNYLTVIRM LITKIPQYFI
PFWYGKEPMF WLPYGWFPYY AEWIISFPRA PMGSVSAPSW QLACSGVITL LGEIIMFAGR
QIFAQPKTKV AQPAEKANKP GKQTAEKSEE KKEL
//
