ID   E9EI45_METAQ            Unreviewed;      1307 AA.
AC   E9EI45;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=DNA repaire protein UVS6 {ECO:0000313|EMBL:EFY84416.1};
GN   ORFNames=MAC_09543 {ECO:0000313|EMBL:EFY84416.1};
OS   Metarhizium acridum (strain CQMa 102).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX   NCBI_TaxID=655827 {ECO:0000313|Proteomes:UP000002499};
RN   [1] {ECO:0000313|EMBL:EFY84416.1, ECO:0000313|Proteomes:UP000002499}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CQMa 102 {ECO:0000313|EMBL:EFY84416.1,
RC   ECO:0000313|Proteomes:UP000002499};
RX   PubMed=21253567; DOI=10.1371/journal.pgen.1001264;
RA   Gao Q., Jin K., Ying S.H., Zhang Y., Xiao G., Shang Y., Duan Z., Hu X.,
RA   Xie X.Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., Fang W., Wang S.,
RA   Zhong Y., Ma L.J., St Leger R.J., Zhao G.P., Pei Y., Feng M.G., Xia Y.,
RA   Wang C.;
RT   "Genome sequencing and comparative transcriptomics of the model
RT   entomopathogenic fungi Metarhizium anisopliae and M. acridum.";
RL   PLoS Genet. 7:E1001264-E1001264(2011).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the SMC family. RAD50 subfamily.
CC       {ECO:0000256|ARBA:ARBA00009439}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL698628; EFY84416.1; -; Genomic_DNA.
DR   RefSeq; XP_007815883.1; XM_007817692.1.
DR   STRING; 655827.E9EI45; -.
DR   GeneID; 19253854; -.
DR   KEGG; maw:MAC_09543; -.
DR   eggNOG; KOG0962; Eukaryota.
DR   HOGENOM; CLU_006184_0_0_1; -.
DR   InParanoid; E9EI45; -.
DR   OMA; FSDYYYR; -.
DR   OrthoDB; 5477220at2759; -.
DR   Proteomes; UP000002499; Unassembled WGS sequence.
DR   GO; GO:0030870; C:Mre11 complex; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   InterPro; IPR004584; Rad50_eukaryotes.
DR   NCBIfam; TIGR00606; rad50; 1.
DR   PANTHER; PTHR18867:SF12; DNA REPAIR PROTEIN RAD50; 1.
DR   PANTHER; PTHR18867; RAD50; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   Pfam; PF13558; SbcC_Walker_B; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002499};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          6..242
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          187..252
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          298..346
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          389..420
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          577..614
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          744..819
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          843..915
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          977..1074
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1307 AA;  149782 MW;  BD743E133A91DAF7 CRC64;
     MSRIDKLSIS GVRSFSPSVR EAIQFNTPLT LIVGYNGSGK TTIIECLKYA TTGELPPNSK
     GGAFIHDPKL CGEKEVMAQV KLQFRSINDR QHVATRSLQL TVKKTTRSQK TLDCSLVVVN
     NGERTTTSTR QAQLDEMIPE RLGVSPAILD AVIFCHQDES LWPLSEPAAL KKRFDEIFEA
     LKYTKAIDNL KVLRKKHVEQ LGKLQNDEAH NKANKDRGER AEKRMTGLQA EIEDAREKCE
     ALSAEMQETH DKIRRKYEQA NSFLQIVQNV GNKKEQLEYR QDAVNELKQT FDELHEDDAS
     LETALAQYEN SMERYREEAE QSKSQYNDLQ QELADSRKNL STKLSEQGKH QSDKDKYERQ
     VKARMEMLQE AAVTHGFRGY DRDLTEHHVK SFNEKIQKLL AEKKRDLERL QKENAAELDK
     ATGVITELEG RKAARTQDRV SAKQRIGAIE KRTSVLQNEA SLIDVDEGAK AILDGQLEDI
     CARFSRAQAQ MEQANWDQHI SDENDKLWQL ETENEKLGRE LVECTRLASE RAQLDYRKKE
     VADRKRKLET LTNTWKSKLA TAIGSDWELD TLETKFHTVL TQQNKALQDA RRSLEQAKQK
     QQKVEYRLKN ARESQESKSR DAETCKKQVL TALHKVRDGA VIDDYQEEVG SVEQQVEDYR
     NELSLFDALV DYYSKCKRML ESKKRCLLCE RHFDDGQSAS LDRLSKKIEK NLDPKGKVDV
     EKDLKEAMAS LDSLRSVRSS YDTYKRLTAE LPSIRDECKA IESEYDALER QLEEHESRVA
     GEDGRVRDLD DLSKTVSSVS QLMKDIQDSE SQVDRIMSQQ LSGGTTRSAD EIHELQASIG
     EQMRGLKNRV AKLTTDRQRM KDQLGSLELE RSELRNKIGQ AVGQLDKKND IQNQIQALRD
     DMIHQRETIQ RADEELEKVE PSIVDARSAR DDTLRRGRAK EQVIVDERDV IANSVSEMKL
     LDNDIQDYID RGGPSNLASN QRAIAALEKS ISNTEKDIAD LTVRANKLKQ DIDSGDRMKK
     NISDNLNYRK HLRQLEVLRR EIEELEDRNA HEDYERLQSE ARSLENQSNR LLAERGSVMG
     SMKTKDEELG RLLQEWEMDY KGAKQKYRES HIRVETTKAA IEDLAQCGAA VDKAVMQFHS
     MKMAEVNRIA GELWQSTYQG TDIDTILIRS DNESTSGKRN YNYRLCMVKQ DTEMDMRGRC
     SAGQKVLASI IIRLALAESF GVNCGLIALD EPTTNLDRDN IKSLAESLHM IIKTRQAQSN
     FQLIVITHDE DFLRHMRCSD FCDSFFRVKR DATQNSVIVR ESITKIF
//